Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance
High producing dairy cows generally receive in the diet up to 5–6% of fat. This is a relatively
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …
[HTML][HTML] Integrated physiology and systems biology of PPARα
S Kersten - Molecular metabolism, 2014 - Elsevier
Abstract The Peroxisome Proliferator Activated Receptor alpha (PPARα) is a transcription
factor that plays a major role in metabolic regulation. This review addresses the functional …
factor that plays a major role in metabolic regulation. This review addresses the functional …
Mitochondrial integrity regulated by lipid metabolism is a cell-intrinsic checkpoint for Treg suppressive function
CS Field, F Baixauli, RL Kyle, DJ Puleston… - Cell metabolism, 2020 - cell.com
Regulatory T cells (Tregs) subdue immune responses. Central to Treg activation are
changes in lipid metabolism that support their survival and function. Fatty acid binding …
changes in lipid metabolism that support their survival and function. Fatty acid binding …
[HTML][HTML] Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation
An in vivo model of antiangiogenic therapy allowed us to identify genes upregulated by
bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of …
bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of …
Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism
CD36 (cluster of differentiation 36) is a scavenger receptor that functions in high-affinity
tissue uptake of long-chain fatty acids (FAs) and contributes under excessive fat supply to …
tissue uptake of long-chain fatty acids (FAs) and contributes under excessive fat supply to …
Peroxisome proliferator‐activated receptor alpha target genes
The peroxisome proliferator‐activated receptor alpha (PPARα) is a ligand‐activated
transcription factor involved in the regulation of a variety of processes, ranging from …
transcription factor involved in the regulation of a variety of processes, ranging from …
The human fatty acid-binding protein family: evolutionary divergences and functions
RL Smathers, DR Petersen - Human genomics, 2011 - Springer
Fatty acid-binding proteins (FABPs) are members of the intracellular lipid-binding protein
(iLBP) family and are involved in reversibly binding intracellular hydrophobic ligands and …
(iLBP) family and are involved in reversibly binding intracellular hydrophobic ligands and …
Peroxisome proliferator-activated receptor α target genes
Peroxisome proliferator-activated receptors (PPARs) are nuclear proteins that belong to the
superfamily of nuclear hormone receptors. They mediate the effects of small lipophilic …
superfamily of nuclear hormone receptors. They mediate the effects of small lipophilic …
Arylfluorosulfates inactivate intracellular lipid binding protein (s) through chemoselective SuFEx reaction with a binding site Tyr residue
Arylfluorosulfates have appeared only rarely in the literature and have not been explored as
probes for covalent conjugation to proteins, possibly because they were assumed to …
probes for covalent conjugation to proteins, possibly because they were assumed to …
Role of the gut in lipid homeostasis
NA Abumrad, NO Davidson - Physiological reviews, 2012 - journals.physiology.org
Intestinal lipid transport plays a central role in fat homeostasis. Here we review the pathways
regulating intestinal absorption and delivery of dietary and biliary lipid substrates, principally …
regulating intestinal absorption and delivery of dietary and biliary lipid substrates, principally …