FDA-approved trifluoromethyl group-containing drugs: a review of 20 years

AS Nair, AK Singh, A Kumar, S Kumar, S Sukumaran… - Processes, 2022 - mdpi.com
As people around the world regard 2020 as the year of COVID-19, the medical community
considers this year to be the second-best year, shared with the year 1996, with respect to the …

Quinolines and quinolones as antibacterial, antifungal, anti-virulence, antiviral and anti-parasitic agents

L Senerovic, D Opsenica, I Moric, I Aleksic… - … Infectious Diseases and …, 2020 - Springer
Infective diseases have become health threat of a global proportion due to appearance and
spread of microorganisms resistant to majority of therapeutics currently used for their …

Tafenoquine-atovaquone combination achieves radical cure and confers sterile immunity in experimental models of human babesiosis

P Vydyam, AC Pal, I Renard, M Chand… - The Journal of …, 2024 - academic.oup.com
Human babesiosis is a potentially fatal tick-borne disease caused by intraerythrocytic
Babesia parasites. The emergence of resistance to recommended therapies highlights the …

Tafenoquine: first global approval

JE Frampton - Drugs, 2018 - Springer
Abstract Tafenoquine (Krintafel™, Arakoda™), an orally-active 8-aminoquinoline anti-
malarial drug, is a long-acting analogue of primaquine with activity against pre-erythrocytic …

Recent Advances in Transition‐Metal‐Catalyzed C− H Functionalization of Ferrocene Amides

Q Mou, R Zhao, B Sun - Chemistry–An Asian Journal, 2022 - Wiley Online Library
During the past decades, in synthetic organic chemistry, directing‐group‐assisted C− H
functionalization is found to be a key tool for the expedient and site‐selective construction of …

The cinchona alkaloids and the aminoquinolines

SL Rawe, C McDonnell - Antimalarial Agents, 2020 - Elsevier
The bark of the cinchona tree was first employed to treat malaria in Europe during the 15th
century. Its active ingredients are natural products that are collectively known as the …

[PDF][PDF] A SYSTEMATIC REVIEW ON MALARIA DISEASE AND ITS TREATMENTS FOCUS ON ARTEMETHER DRUG

SD PHALAK, V BODKE, R YADAV, S PANDAV… - Int J Curr Pharm …, 2024 - academia.edu
Malaria is one of the infectious illnesses of the highest scientific significance and importance
to international health organizations. Plasmodium falciparum, the parasite responsible for a …

Mosquito-borne diseases

MA Saleem, I Lobanova - Dengue Virus Disease, 2020 - Elsevier
Despite our best eradication efforts, mosquitoes stay as a substantial infectious threat to the
modern civilization affecting not only humans but other groups of animals as well. Their …

Discovery and Trends of 8‐Aminoquinoline and 4‐Aminoquinoline Classes of Antimalarials

M Jain, S Das, R Jain - Drug Development for Malaria: Novel …, 2022 - Wiley Online Library
Malaria is a gruesome disease caused by Plasmodium parasites and poses a major medical
risk in large parts of the world. The development of new, affordable antimalarial drugs is of …

Discovery of brussonol analogs as lead candidates for malaria

CS Barbosa - 2024 - teses.usp.br
Malaria is a disease caused by Plasmodium parasites affecting millions of people globally.
Different strategies were applied throughout the years to decrease malaria burden, however …