[HTML][HTML] Specialized pro-resolving mediators: endogenous regulators of infection and inflammation

MC Basil, BD Levy - Nature Reviews Immunology, 2016 - nature.com
Specialized pro-resolving mediators (SPMs) are enzymatically derived from essential fatty
acids and have important roles in orchestrating the resolution of tissue inflammation—that is …

Bioactive lipids, inflammation and chronic diseases

A Leuti, D Fazio, M Fava, A Piccoli, S Oddi… - Advanced Drug Delivery …, 2020 - Elsevier
Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …

The role of smoking in the mechanisms of development of chronic obstructive pulmonary disease and atherosclerosis

S Kotlyarov - International Journal of Molecular Sciences, 2023 - mdpi.com
Tobacco smoking is a major cause of chronic obstructive pulmonary disease (COPD) and
atherosclerotic cardiovascular disease (ASCVD). These diseases share common …

Maresin 1, a proresolving lipid mediator derived from omega-3 polyunsaturated fatty acids, exerts protective actions in murine models of colitis

R Marcon, AF Bento, RC Dutra, MA Bicca… - The Journal of …, 2013 - journals.aai.org
It has been previously reported that dietary fish oils, which are rich in the polyunsaturated
fatty acids eicosapentaenoic acid and docosahexaenoic acid, can exert beneficial effects in …

Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: Mechanisms and development

A Yang, Y Wu, G Yu, H Wang - Respiratory Research, 2021 - Springer
Inflammation is an essential mechanism of various diseases. The development and
resolution of inflammation are complex immune-modulation processes which induce the …

Diagnosis, prognosis, and treatment of canine hemangiosarcoma: a review based on a consensus organized by the Brazilian association of veterinary oncology …

AB De Nardi, C de Oliveira Massoco Salles Gomes… - Cancers, 2023 - mdpi.com
Simple Summary Hemangiosarcoma is a mesenchymal neoplasm that originates in the
endothelial cells of blood vessels. According to the location of origin, they can be classified …

Proresolving lipid mediators: endogenous modulators of oxidative stress

A Leuti, M Maccarrone… - Oxidative medicine and …, 2019 - Wiley Online Library
Specialized proresolving mediators (SPMs) are a novel class of endogenous lipids, derived
by ω‐6 and ω‐3 essential polyunsaturated fatty acids such as arachidonic acid (AA) …

Neuroinflammation, oxidative stress and their interplay in neuropathic pain: Focus on specialized pro-resolving mediators and NADPH oxidase inhibitors as potential …

L Teixeira-Santos, A Albino-Teixeira, D Pinho - Pharmacological Research, 2020 - Elsevier
Neuropathic pain (NP) is a chronic condition that results from a lesion or disease of the
nervous system, greatly impacting patients' quality of life. Current pharmacotherapy options …

Roles of resolvins in chronic inflammatory response

C Liu, D Fan, Q Lei, A Lu, X He - International journal of molecular …, 2022 - mdpi.com
An inflammatory response is beneficial to the organism, while an excessive uncontrolled
inflammatory response can lead to the nonspecific killing of tissue cells. Therefore …

Specialized proresolving mediators in innate and adaptive immune responses in airway diseases

N Krishnamoorthy, REE Abdulnour… - Physiological …, 2018 - journals.physiology.org
Airborne pathogens and environmental stimuli evoke immune responses in the lung. It is
critical to health that these responses be controlled to prevent tissue damage and the …