Die Aufgabe des Immunsystems ist es unter anderem fremde und defekte Zellen zu
erkennen und auszuschalten. Tumorzellen können sich mit verschiedenen Mechanismen …

Die ambulant erworbene Pneumonie ist mit ihrer hohen Inzidenz und Mortalität eine der
bedeutendsten Infektionskrankheiten weltweit. Streptococcus pneumoniae (S. pn.) ist der …

Strict and facultative anaerobic bacteria are widely associated with both acute and chronic
airway disease. However, their potential role (s) in disease pathophysiology remain poorly …

All type of implantations, especially for non-resorptive materials (metallic, hard insoluble
polymers) involve an inflammatory response, followed by wound healing reaction …

Background: Primary Sjögren's syndrome (pSS) and systemic lupus erythematosus (SLE)
are chronic autoimmune rheumatic diseases (ARDs) that share a strong female gender bias …

Background: Lupus nephritis (LN) is a condition arising from abnormal immune responses to
internal organs. Patients with LN suffer from severe morbidity and mortality 1, 2. Despite the …

The resurgence of haploidentical stem cell transplantation (HaploSCT) over the last decade
is one of the most important advances in the field of hematopoietic stem cell transplantation …

Background: SLE is heterogeneous in clinical presentation, underlying immunology, and
response to therapy. Patients with severe or resistant disease receive cyclophosphamide or …

Controlled opening of endothelial-cell (EC) junctions is vital in regulating vascular
permeability and neutrophil transendothelial migration (TEM) during acute inflammation …

Abstract Tumor progression locus 2 (Tpl2, MAP3K8, COT) is a serine threonine kinase
known to regulate inflammation in a variety of infections, cancers, and autoimmune …