Oxytocin system dysfunction as a common mechanism underlying metabolic syndrome and psychiatric symptoms in schizophrenia and bipolar disorders

DS Quintana, I Dieset, T Elvsåshagen… - Frontiers in …, 2017 - Elsevier
There is growing interest in using intranasal oxytocin (OT) to treat social dysfunction in
schizophrenia and bipolar disorders (ie, psychotic disorders). While OT treatment results …

Oxytocin fails to recruit serotonergic neurotransmission in the autistic brain

A Lefevre, R Mottolese, J Redouté, N Costes… - Cerebral …, 2018 - academic.oup.com
Oxytocin (OT), a neuropeptide involved in affiliation has been shown to enhance social skills
in patients with autism spectrum disorders (ASD). Nevertheless, OT improvements seem …

Oxytocin and borderline personality disorder

K Bertsch, SC Herpertz - Behavioral pharmacology of neuropeptides …, 2017 - Springer
Borderline personality disorder (BPD) is a prevalent and severe mental disorder with affect
dysregulation, impulsivity, and interpersonal dysfunction as its core features. Up to now, six …

Oxytocin regulates reunion affiliation with a pairmate following social separation in marmosets

J Cavanaugh, A Mustoe… - American Journal of …, 2018 - Wiley Online Library
While separation from significant social partners produces a host of neurobiological and
behavioral perturbations, including behavioral distress and increased glucocorticoid …

Effects of intraperitoneal and intracerebroventricular injections of oxytocin on social and emotional behaviors in pubertal male mice

T Sakamoto, S Sugimoto, T Uekita - Physiology & behavior, 2019 - Elsevier
Oxytocin plays important roles in the social and emotional behaviors of mammals. In the
present study, we examined the effects of intraperitoneal (IP) and intracerebroventricular …

Measuring peripheral oxytocin and vasopressin in nonhuman primates

TE Ziegler - American Journal of Primatology, 2018 - Wiley Online Library
Studying the neural and hormonal changes that modulate behavior is critical to
understanding social relationships. Of particular interest is measuring oxytocin (OT) and …

Safety and tolerability of chronic intranasal oxytocin in older men: results from a randomized controlled trial

JM Rung, M Horta, EM Tammi, E Perez, MC Ojeda… - …, 2021 - Springer
Rationale Most studies evaluating the safety and tolerability of intranasal oxytocin (OT) have
not reported consistent adverse events (AEs), but they have largely focused on young men …

Effects of oxytocin on serotonin 1B agonist-induced autism-like behavior in mice

SK Lawson, AC Gray, NS Woehrle - Behavioural brain research, 2016 - Elsevier
Social impairments in autism remain poorly understood and without approved
pharmacotherapies. Novel animals models are needed to elucidate mechanisms and …

The role of oxytocin in parenting and as augmentative pharmacotherapy: critical issues and bold conjectures

MH van IJzendoorn… - Journal of …, 2016 - Wiley Online Library
Despite the sometimes heated debate about the validity of human oxytocin studies,
experimental oxytocin research with intranasal administration is a growing field with …

[HTML][HTML] How oxytocin receptor (OXTR) single nucleotide polymorphisms act on prosociality: the mediation role of moral evaluation

S Shang, N Wu, Y Su - Frontiers in Psychology, 2017 - frontiersin.org
Prosociality is related to numerous positive outcomes, and mechanisms underlying
individual differences in prosociality have been widely discussed. Recently, research has …