Alzheimer's disease (AD) has characteristic histopathological, molecular, and biochemical
abnormalities, including cell loss; abundant neurofibrillary tangles; dystrophic neurites; …

Context Although acute hypoglycemia may be associated with cognitive impairment in
children with type 1 diabetes, no studies to date have evaluated whether hypoglycemia is a …

Context Chronic obesity is associated with several complications, including cognitive
impairment and dementia. However, we have only piecemeal knowledge of the mechanisms …

Alzheimer's disease [AD] is the most common cause of dementia in North America. Despite
30+ years of intense investigation, the field lacks consensus regarding the etiology and …

BACKGROUND: Late-onset Alzheimer's disease (AD) is a multifactorial and heterogeneous
disorder with major risk factors including advanced age, presence of an apolipoprotein E ε4 …

Background: Numerous reports show that a centralized distribution of adiposity is a more
dangerous risk factor for cardiovascular disease and diabetes than total body obesity. No …

Objective: The relation of overweight to dementia is controversial. We aimed to examine the
association of midlife overweight and obesity with dementia, Alzheimer disease (AD), and …

Abstract Background Approximately 70% of Alzheimer's disease (AD) patients have co-
morbid vascular contributions to cognitive impairment and dementia (VCID); this highly …

Being overweight or obese, as measured with body-mass index or central adiposity (waist
circumference), and the trajectory of body-mass index over the life course have been …

The increase in life expectancy has resulted in a high occurrence of dementia and
Alzheimer's disease (AD). Research on AD has undergone a paradigm shift from viewing it …