Summary While dementia affects 6–10% of persons 65 years or older, industrialized
countries have witnessed an alarming rise in obesity. However, obesity's influence on …

Obesity is defined as abnormal and excessive fat accumulation, and it is a risk factor for
developing metabolic and neurodegenerative diseases and cognitive deficits. Obesity is …

Controversies persist about the associations of body mass index (BMI) with risk of cognitive
impairment and dementia. This study aimed to evaluate these associations from various …

Alzheimer's disease and other related neurodegenerative diseases are highly debilitating
disorders that affect millions of people worldwide. Efforts towards developing effective …

Aging and metabolism-related disorders are risk factors for Alzheimer disease (AD).
Because sirtuins may increase the life span through regulation of cellular metabolism, we …

The World Health Organisation has estimated that by 2015 approximately 2.3 billion adults
will be overweight and more than 700 million obese. Obesity is associated with an increased …

Objectives This review focuses on the relationship between obesity and aging and how
these interact to affect cognitive function. The topics covered are guided by the Scaffolding …

The increasing ageing of our societies is accompanied by a pandemic of obesity and related
cardiometabolic disorders. Progressive dysfunction of the white adipose tissue is …

Vascular risk factors, such as type 2 diabetes mellitus, hypertension, dyslipidemia and
obesity, have been associated with an increased risk of cognitive dysfunction, particularly in …

Background: Obesity has been consistently associated with dementia. The role of certain
risk factors of dementia may change during life, and the importance of having a life-course …