Exercise Is More Effective than Diet Control in Preventing High Fat Diet-induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic …

M Maesako, K Uemura, M Kubota, A Kuzuya… - Journal of Biological …, 2012 - ASBMB
Accumulating evidence suggests that some dietary patterns, specifically high fat diet (HFD),
increase the risk of developing sporadic Alzheimer disease (AD). Thus, interventions …

Sex differences in metabolic phenotype and hypothalamic inflammation in the 3xTg-AD mouse model of Alzheimer's disease

LS Robison, OJ Gannon, AE Salinero… - Biology of Sex …, 2023 - Springer
Background Alzheimer's disease (AD) is notably associated with cognitive decline resulting
from impaired function of hippocampal and cortical areas; however, several other domains …

Pathways linking obesity to neuropsychiatric disorders

LB Martins, NM Monteze, C Calarge, AVM Ferreira… - Nutrition, 2019 - Elsevier
Obesity has been associated with cognitive and behavioral syndromes. Individuals who are
obese have higher risk for developing neuropsychiatric disorders such as depression and …

Perimenopause and cognition

GA Greendale, CA Derby… - … and Gynecology Clinics, 2011 - obgyn.theclinics.com
Is the perimenopausal transition detrimental to cognitive function? This is an often-asked
question in clinical practice, because self-reported memory problems are common during …

Insulin sensitivity as a mediator of the relationship between BMI and working memory‐related brain activation

MM Gonzales, T Tarumi, SC Miles, H Tanaka, F Shah… - …, 2010 - Wiley Online Library
Midlife obesity is associated with cognitive deficits and cerebral atrophy in older age.
However, little is known about the early signs of these deleterious brain effects or the …

Is there chronic brain damage in retired NFL players? Neuroradiology, neuropsychology, and neurology examinations of 45 retired players

IR Casson, DC Viano, EM Haacke, Z Kou… - Sports …, 2014 - journals.sagepub.com
Background: Neuropathology and surveys of retired National Football League (NFL) players
suggest that chronic brain damage is a frequent result of a career in football. There is limited …

Sex-specific effects of high fat diet on indices of metabolic syndrome in 3xTg-AD mice: implications for Alzheimer's disease

AM Barron, ER Rosario, R Elteriefi, CJ Pike - PloS one, 2013 - journals.plos.org
Multiple factors of metabolic syndrome have been implicated in the pathogenesis of
Alzheimer's disease (AD), including abdominal obesity, insulin resistance, endocrine …

Obesity and lowered cognitive performance in a Canadian First Nations population

JH Fergenbaum, S Bruce, W Lou, AJG Hanley… - …, 2009 - Wiley Online Library
The association between obesity, other cardiovascular risk factors, and cognitive function in
a Canadian First Nations population was investigated using a cross‐sectional design …

Post-traumatic stress disorder and risk of dementia among members of a health care delivery system

JD Flatt, P Gilsanz, CP Quesenberry Jr, KB Albers… - Alzheimer's & …, 2018 - Elsevier
Introduction Post-traumatic stress disorder (PTSD) is associated with an increased risk of
dementia in male veterans, but little is known in females and civilians. Methods PTSD and …

Obesity, leptin, and Alzheimer's disease

EB Lee - Annals of the New York Academy of Sciences, 2011 - Wiley Online Library
Obesity has various deleterious effects on health largely associated with metabolic
abnormalities including abnormal glucose and lipid homeostasis that are associated with …