[HTML][HTML] Pathophysiology of obesity and its associated diseases

X Jin, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023 - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

[HTML][HTML] Recent advances in the knowledge of the mechanisms of leptin physiology and actions in neurological and metabolic pathologies

ME Casado, R Collado-Pérez, LM Frago… - International Journal of …, 2023 - mdpi.com
Excess body weight is frequently associated with low-grade inflammation. Evidence
indicates a relationship between obesity and cancer, as well as with other diseases, such as …

Emerging mechanisms of obesity-associated immune dysfunction

SR Shaikh, MA Beck, Y Alwarawrah… - Nature Reviews …, 2024 - nature.com
Obesity is associated with a wide range of complications, including type 2 diabetes mellitus,
cardiovascular disease, hypertension and nonalcoholic fatty liver disease. Obesity also …

[HTML][HTML] The role of selected adipocytokines in ovarian cancer and endometrial cancer

S Stępień, P Olczyk, J Gola, K Komosińska-Vassev… - Cells, 2023 - mdpi.com
Due to their multidirectional influence, adipocytokines are currently the subject of numerous
intensive studies. Significant impact applies to many processes, both physiological and …

[HTML][HTML] Role of leptin and adiponectin in carcinogenesis

A Bocian-Jastrzębska, A Malczewska-Herman… - Cancers, 2023 - mdpi.com
Simple Summary The involvement of leptin and adiponectin with receptors in the formation
of many types of cancer as well as their impact on the clinical course of cancer patients are …

[HTML][HTML] Role of Leptin as a link between Asthma and Obesity: A systematic Review and Meta-Analysis

H Sánchez-Ortega, C Jiménez-Cortegana… - International Journal of …, 2022 - mdpi.com
Asthma and obesity are considered as highly prevalent diseases with a great impact on
public health. Obesity has been demonstrated to be an aggravating factor in the …

[HTML][HTML] Obesity and Risk for Lymphoma: Possible Role of Leptin

C Jiménez-Cortegana, L Hontecillas-Prieto… - International Journal of …, 2022 - mdpi.com
Obesity, which is considered a pandemic due to its high prevalence, is a risk factor for many
types of cancers, including lymphoma, through a variety of mechanisms by promoting an …

[HTML][HTML] Infection and immunometabolism in the central nervous system: a possible mechanistic link between metabolic imbalance and dementia

N Shinjyo, K Kita - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Metabolic syndromes are frequently associated with dementia, suggesting that the
dysregulation of energy metabolism can increase the risk of neurodegeneration and …

[HTML][HTML] Lifespan extension in long-lived vertebrates rooted in ecological adaptation

O Omotoso, VN Gladyshev, X Zhou - Frontiers in Cell and …, 2021 - frontiersin.org
Contemporary studies on aging and longevity have largely overlooked the role that
adaptation plays in lifespan variation across species. Emerging evidence indicates that the …

[HTML][HTML] Insight on the role of leptin: a bridge from obesity to breast cancer

R Buonaiuto, F Napolitano, S Parola, P De Placido… - Biomolecules, 2022 - mdpi.com
Leptin is a peptide hormone, mainly known for its role as a mediator of adipose tissue
endocrine functions, such as appetite control and energy homeostasis. In addition, leptin …