Generation of tamoxifen‐inducible Tfap2b‐CreERT2 mice using CRISPR‐Cas9
Tfap2b, a pivotal transcription factor, plays critical roles within neural crest cells and their
derived lineage. To unravel the intricate lineage dynamics and contribution of these Tfap2b+ …
derived lineage. To unravel the intricate lineage dynamics and contribution of these Tfap2b+ …
Reverse genetic screening during L1 arrest reveals a role of the diacylglycerol kinase 1 gene dgk-1 and sphingolipid metabolism genes in sleep regulation
A Koutsoumparis, I Busack, CK Chen, Y Hayashi… - Genetics, 2023 - academic.oup.com
Sleep is a fundamental state of behavioral quiescence and physiological restoration. Sleep
is controlled by environmental conditions, indicating a complex regulation of sleep by …
is controlled by environmental conditions, indicating a complex regulation of sleep by …
[HTML][HTML] Crucial role of TFAP2B in the nervous system for regulating NREM sleep
A Nakai, M Kashiwagi, T Fujiyama, K Iwasaki, A Hirano… - Molecular brain, 2024 - Springer
The AP-2 transcription factors are crucial for regulating sleep in both vertebrate and
invertebrate animals. In mice, loss of function of the transcription factor AP-2β (TFAP2B) …
invertebrate animals. In mice, loss of function of the transcription factor AP-2β (TFAP2B) …
[HTML][HTML] Structural neuroplasticity after sleep loss modifies behavior and requires neurexin and neuroligin
Structural neuroplasticity (changes in the size, strength, number, and targets of synaptic
connections) can be modified by sleep and sleep disruption. However, the causal …
connections) can be modified by sleep and sleep disruption. However, the causal …