Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis
AS Nagle, S Khare, AB Kumar, F Supek… - Chemical …, 2014 - ACS Publications
Leishmaniasis is a parasitic disease that presents four main clinical syndromes: cutaneous
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …
Leishmaniasis diagnosis: an update on the use of parasitological, immunological and molecular methods
Diagnosis of leishmaniasis has always been a major challenge as its clinical features
resemble some other commonly occurring diseases such as tuberculosis, typhoid, and …
resemble some other commonly occurring diseases such as tuberculosis, typhoid, and …
Role of cytokines in experimental and human visceral leishmaniasis
Visceral Leishmaniasis (VL) is the most fatal form of disease leishmaniasis. To date, there
are no effective prophylactic measures and therapeutics available against VL. Recently, new …
are no effective prophylactic measures and therapeutics available against VL. Recently, new …
Diagnosis of visceral leishmaniasis: developments over the last decade
G Srividya, A Kulshrestha, R Singh, P Salotra - Parasitology research, 2012 - Springer
Diagnostic parameters for visceral leishmaniasis (VL), a potentially fatal parasitic disease
caused by Leishmania donovani, have been redefined in the last decade with the …
caused by Leishmania donovani, have been redefined in the last decade with the …
[HTML][HTML] Visceral leishmaniasis: a global overview
RG Wamai, J Kahn, J McGloin, G Ziaggi - Journal of Global Health …, 2020 - e-jghs.org
The leishmaniases are protozoan infections that are among the neglected tropical diseases
(NTDs). Over one billion people are at risk of these diseases in virtually all continents. These …
(NTDs). Over one billion people are at risk of these diseases in virtually all continents. These …
A novel mechanism for an old drug: amphotericin B in the treatment of visceral leishmaniasis
A Chattopadhyay, M Jafurulla - Biochemical and biophysical research …, 2011 - Elsevier
Visceral leishmaniasis (VL) is caused by various species of the genus Leishmania.
Internalization of Leishmania into host cells is facilitated by a large number of receptors, and …
Internalization of Leishmania into host cells is facilitated by a large number of receptors, and …
Developments in diagnosis of visceral leishmaniasis in the elimination era
Visceral leishmaniasis (VL) is the most devastating parasitic infection worldwide causing
high morbidity and mortality. Clinical presentation of VL ranges from asymptomatic or …
high morbidity and mortality. Clinical presentation of VL ranges from asymptomatic or …
Risk factors for adverse prognosis and death in American visceral leishmaniasis: a meta-analysis
Background In the current context of high fatality rates associated with American visceral
leishmaniasis (VL), the appropriate use of prognostic factors to identify patients at higher risk …
leishmaniasis (VL), the appropriate use of prognostic factors to identify patients at higher risk …
Nanotechnology-based strategies in parasitic disease management: from prevention to diagnosis and treatment
Parasitic infections are a major global health issue causing significant mortality and
morbidity. Despite substantial advances in the diagnostics and treatment of these diseases …
morbidity. Despite substantial advances in the diagnostics and treatment of these diseases …
Evaluating drug resistance in visceral leishmaniasis: the challenges
For decades antimonials were the drugs of choice for the treatment of visceral leishmaniasis
(VL), but the recent emergence of resistance has made them redundant as first-line therapy …
(VL), but the recent emergence of resistance has made them redundant as first-line therapy …