Chronic inflammation is linked to the development of multiple cancers, including those of the
colon. Inflammation in the gut induces carcinogenic mutagenesis and promotes colorectal …

Colorectal cancer (CRC) is the third most common diagnosed malignancy among both
sexes in the United States as well as in the European Union. While the incidence and …

Whether dietary fiber protects against colorectal cancer is controversial because of
conflicting results from human epidemiologic studies. However, these studies and mouse …

Colorectal cancer (CRC) is a major health problem in industrialized countries. Although
inflammation-linked carcinogenesis is a well accepted concept and is often observed within …

Although metabolic adaptations have been demonstrated to be essential for tumor cell
proliferation, the metabolic underpinnings of tumor initiation are poorly understood. We …

Chronic inflammation, regardless of infectious agents, plays important roles in the
development of various cancers, particularly in digestive organs, including Helicobacter …

Background The knowledge on the mechanisms through which the metabolites produced by
the gut microbiota (postbiotics) prevent diseases, induce therapeutic responses, and behave …

Immunotherapies targeting T lymphocytes are revolutionizing cancer therapy but only
benefit a subset of patients, especially in colorectal cancer. Thus, additional insight into the …

The innate immune system provides first-line defences in response to invading
microorganisms and endogenous danger signals by triggering robust inflammatory and …

Cancers of the colon are most common in the Western world. In majority of these cases,
there is no familial history and sporadic gene damage seems to play an important role in the …