Clinical management of primary biliary cholangitis—strategies and evolving trends

L Gao, L Wang, E Woo, XS He, GX Yang… - Clinical reviews in …, 2020 - Springer
PBC is a chronic progressive autoimmune disorder involving the destruction of intrahepatic
small bile ducts, cholestasis, fibrosis, and ultimately cirrhosis if left untreated. It is largely …

[HTML][HTML] Cholestatic liver injury induced by food additives, dietary supplements and parenteral nutrition

V Vilas-Boas, E Gijbels, J Jonckheer, E De Waele… - Environment …, 2020 - Elsevier
Cholestasis refers to the accumulation of toxic levels of bile acids in the liver due to defective
bile secretion. This pathological situation can be triggered by drugs, but also by ingredients …

Mesenchymal stem cells as new therapeutic agents for the treatment of primary biliary cholangitis

A Arsenijevic, CR Harrell, C Fellabaum… - Analytical Cellular …, 2017 - Wiley Online Library
Primary biliary cholangitis (PBC) is a chronic autoimmune cholestatic liver disease
characterized by the progressive destruction of small‐and medium‐sized intrahepatic bile …

The autoimmune susceptibility gene C5orf30 regulates macrophage-mediated resolution of inflammation

ER Dorris, SJ Tazzyman, J Moylett… - The Journal of …, 2019 - journals.aai.org
Genetic variants in C5orf30 have been associated with development of the autoimmune
conditions primary biliary cirrhosis and rheumatoid arthritis. In rheumatoid arthritis, C5orf30 …

[PDF][PDF] Genetic Risk Factors for Autoimmune Thyroid Disease might Affect the Susceptibility to and Modulate the Progression of Primary Biliary Cholangitis.

A Kuś, M Arłukowicz-Grabowska… - … of Gastrointestinal & …, 2017 - researchgate.net
ABSTRACT Background & Aims: Patients with primary biliary cholangitis (PBC) frequently
suffer from extrahepatic autoimmune conditions, of which autoimmune thyroid disease …

Bile acid analog intercepts liver fibrosis

CD De Magalhaes Filho, M Downes, R Evans - Cell, 2016 - cell.com
Ocaliva, a synthetic bile acid analog with high affinity for the nuclear bile acid receptor FXR,
is effective in treating primary biliary cholangitis, an autoimmune liver disease. It works in …

Factors influencing the six-month mortality rate in patients with a hip fracture

T Prodovic, B Ristic, N Rancic, Z Bukumiric… - Slovenian Journal of …, 2016 - sciendo.com
Materials and Methods This study was conducted at the University hospital, which treats all
patients with hip fractures in Sumadija Region (Central Serbia). The study included all …

The clinical value of the monocyte to high-density lipoprotein cholesterol ratio and alkaline phosphatase-to-platelet ratio in primary biliary cholangitis

Y Lao, X Li, W Zhou, H Zhu, Y Jiang, S Li, M Jin… - Medicine, 2023 - journals.lww.com
This study aimed to evaluate the clinical value of the monocyte to high-density lipoprotein
cholesterol ratio (MHR) and alkaline phosphatase-to-platelet ratio (APPR) in the diagnosis …

肝巨噬细胞在原发性胆汁性胆管炎发生发展中的作用.

杨文霞, 唐映梅 - Journal of Clinical Hepatology/Linchuang …, 2020 - search.ebscohost.com
杨文霞,唐映梅 Page 1 肝巨噬细胞在原发性胆汁性胆管炎发生发展中的作用 杨文霞,唐映梅 昆明
医科大学第二附属医院消化内科,昆明650000 摘要:原发性胆汁性胆管炎(PBc)是一种病因未明的以 …

Colangitis biliar primaria. Parte 2. Actualización: diagnóstico, enfermedades asociadas, tratamiento y pronóstico

DA Rodríguez Lugo, JJ Coronado Tovar… - Revista de …, 2018 - scielo.org.pe
La colangitis biliar primaria (CBP), es una colangiopatía crónica caracterizada por la
destrucción selectiva de las células epiteliales biliares de conductos hepáticos de pequeño …