Traumatic brain injury and immunological outcomes: the double-edged killer

S Datta, F Lin, LD Jones, SC Pingle, S Kesari… - Future science …, 2023 - Future Science
Traumatic brain injury (TBI) is a significant cause of mortality and morbidity worldwide
resulting from falls, car accidents, sports, and blast injuries. TBI is characterized by severe …

[HTML][HTML] Controlled oxygen delivery to power tissue regeneration

E Zoneff, Y Wang, C Jackson, O Smith, S Duchi… - Nature …, 2024 - nature.com
Oxygen plays a crucial role in human embryogenesis, homeostasis, and tissue
regeneration. Emerging engineered regenerative solutions call for novel oxygen delivery …

[HTML][HTML] The Pig as a Translational Animal Model for Biobehavioral and Neurotrauma Research

AH Netzley, G Pelled - Biomedicines, 2023 - mdpi.com
In recent decades, the pig has attracted considerable attention as an important intermediary
model animal in translational biobehavioral research due to major similarities between pig …

[HTML][HTML] Proteasome localization and activity in pig brain and in vivo small molecule screening for activators

A Amrein Almira, MW Chen, N El Demerdash… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Loss of proteasome function, proteinopathy, and proteotoxicity may cause
neurodegeneration across the human lifespan in several forms of brain injury and disease …

[HTML][HTML] How Nitric Oxide Hindered the Search for Hemoglobin-Based Oxygen Carriers as Human Blood Substitutes

M Samaja, A Malavalli, KD Vandegriff - International Journal of Molecular …, 2023 - mdpi.com
The search for a clinically affordable substitute of human blood for transfusion is still an
unmet need of modern society. More than 50 years of research on acellular hemoglobin …

Assessment of Behavioral and fMRI Differences in a Minipig Model of Pediatric Concussion

AH Netzley - 2023 - search.proquest.com
Traumatic brain injury (TBI) is a leading cause of death and disability among children and
adolescents in the United States. An estimated 90% of head-injury-related emergency …

[HTML][HTML] Inhibition of metastatic brain cancer in Sonic Hedgehog medulloblastoma using caged nitric oxide albumin nanoparticles

BJ Soltys, KB Grausam, SM Messerli, CJC Hsia… - Frontiers in …, 2023 - frontiersin.org
Medulloblastoma is a tumor of the cerebellum that metastasizes to the leptomeninges of the
central nervous system (CNS), including to forebrain and to spinal cord. The inhibitory effect …