Diffusion MRI (dMRI) is a unique tool for the study of brain circuitry, as it allows us to image
both the macroscopic trajectories and the microstructural properties of axon bundles in vivo …

Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

INTRODUCTION White matter in the human brain serves a critical role in organizing
distributed neural networks. Diffusion magnetic resonance imaging (dMRI) has enabled the …

The gut microbiota is increasingly recognized as a modulator of brain and behavior but its
role in early childhood, when the microbiome and the brain are both undergoing rapid …

Strict iron regulation is essential for normal brain function. The iron homeostasis, determined
by the milieu of available iron compounds, is impaired in aging, neurodegenerative …

Myelin-sensitive MRI such as magnetization transfer imaging has been widely used in
multiple sclerosis. The influence of methodology and differences in disease subtype on …

Conduction velocity is the speed at which electrical signals travel along axons and is a
crucial determinant of neural communication. Inferences about conduction velocity can now …

Peripheral nerve regeneration after injury is still a clinical problem. The application of
autologous nerve grafting, the gold standard treatment, is greatly restricted. Acellular nerve …

The neuronal differences contributing to the etiology of autism spectrum disorder (ASD) are
still not well defined. Previous studies have suggested that myelin and axons are disrupted …

Background Psychomotor disturbance is common in psychotic depression and is associated
with relapse. In this analysis, we examined whether white matter microstructure is …