Peripheral blood biomarkers associated with toxicity and treatment characteristics after 131I-metaiodobenzylguanidine therapy in patients with neuroblastoma

K Campbell, EE Karski, A Olow, DA Edmondson… - International Journal of …, 2017 - Elsevier
Purpose Few tools exist to predict clinical outcomes after radiopharmaceutical therapy. Our
goal was to identify associations between blood-based biomarkers of radiation effect and …

Defining blood processing parameters for optimal detection of γ-H2AX foci: a small blood volume method

M Wojewodzka, S Sommer… - Radiation …, 2015 - meridian.allenpress.com
Biodosimetric methods used to measure the effects of radiation are critical for estimating the
health risks to irradiated individuals or populations. The direct measurement of radiation …

Потенциал использования определения двунитевых разрывов ДНК в различных областях медицины

АВ Торгашина, АМ Лила - Современная ревматология, 2023 - mrj.ima-press.net
Аннотация В статье рассмотрена актуальность определения двунитевых разрывов
ДНК (ДРД) при помощи анализа фокусов γ-H2AX в качестве маркера нестабильности …

A modified fluorimetric neutral filter elution method for analyzing radiation-induced double strand break and repair

VH Goutham, MD Kamalesh, PK Guruprasad… - Analytical …, 2011 - Elsevier
Neutral filter elution assay is one of the methods used for detection of DNA double strand
breaks (DSBs). However, it is laborious, expensive, and hazardous (radiolabeled precursors …

[HTML][HTML] Оценка последствий дистанционной лучевой терапии у больных раком лёгкого путём анализа хромосомных аберраций в лимфоцитах крови

ИК Хвостунов, ЛВ Курсова… - Радиация и риск …, 2019 - cyberleninka.ru
В настоящей работе проведено исследование последствий лучевой терапии больных
раком лёгкого. Оценка последствий выполнялась путём подсчёта аберраций хромосом …

Flow cytometry-assisted quantification of γH2AX expression has potential as a rapid high-throughput biodosimetry tool

DG Achel, AM Serafin, JM Akudugu - Radiation and environmental …, 2016 - Springer
Large-scale radiological events require immediate and accurate estimates of doses
received by victims, and possibly the first responders, to assist in treatment decisions …

Phosphorylation of histone H2AX in peripheral blood mononuclear cells after thoracic irradiation of rats

R Havelek, M Řezáčová, Z Šinkorová… - Journal of Applied …, 2011 - Elsevier
Lymphocytes are among the most radiosensitive cells. After exposure of the organism to
ionizing radiation, they promptly die by apoptosis at a rate proportional to the dose received …

[PDF][PDF] Response of normal cells following multiple radiation exposure under radiotherapy setting

MH Yashavarddhan, S Kumar, A Kumar, M Suar - Def Life Sci J, 2017 - researchgate.net
Cancer is a symptom in which abnormal cells divide in an uncontrolled manner and destroy
body tissue1. Radiotherapy has been commonly used in clinics for treatment of cancer2. The …

[图书][B] Suitability of the γ-H2AX assay for human radiation biodosimetry

S Roch-Lefèvre, M Valente, P Voisin, JF Barquinero - 2012 - academia.edu
For biodosimetry purposes, there are only a few minimally invasive procedures. Two of
them, fast and painless are particularly suited for large scale sample collection. One is to …

[PDF][PDF] Assessment of DNA damage induction in farm animals after the FNPP accident

AJ Nakamura - Low-Dose Radiation Effects on Animals and …, 2020 - library.oapen.org
Abstract Since the Fukushima Daiichi Nuclear Power Plant (FNPP) accident is a radiation
accident which occurred as the aftermath of a devastating natural disaster, the Great East …