Pain due to chronic conditions is a frequent and insufficiently addressed problem. Current
drug options for pain management (either in cases of chronic inflammatory conditions or …

Animal models have been invaluable in the identification of molecular events occurring in
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …

Autophagy is a vacuolar, lysosomal degradation pathway for injured and damaged protein
molecules and organelles in eukaryotic cells, which is controlled by nutrients and stress …

Alzheimer's disease (AD) is one of the most prevailing neurodegenerative diseases in the
world, which is characterized by memory dysfunction and the formation of tau and amyloid β …

Chronic pain and its associated comorbidities are difficult to treat, even when the most
potent analgesic compounds are used. Thus, research on new strategies to effectively …

Chemotherapy-induced peripheral neuropathy (CIPN) is a treatment-limiting adverse effect
of anticancer therapy that complicates the lifestyle of many cancer survivors. There is …

Abstract Ethnopharmacological relevance Anadenanthera colubrina (Vell.) Brenan is an
endemic tree to South America and different parts of it are used by the population for the …

Pain is the most common symptom that dentists are confronted with, whether acute (pulpitis,
acute periodontitis, post-surgery, etc.) or chronic diseases, such as periodontitis, muscle …

The fact that neuropathic pain (NP) has no effective therapy and is frequently accompanied
by psychiatric comorbidities is well established. Aberrant neuroinflammation plays an …

Background and purpose: Peripheral neuropathy is one of the most common adverse effects
of cancer chemotherapy. Vincristine is prescribed to treat a variety of carcinomas, including …