Sex as a biological variable for cardiovascular physiology

ML Lindsey, CW Usselman… - American Journal …, 2024 - journals.physiology.org
There have been ongoing efforts by federal agencies and scientific communities since the
early 1990s to incorporate sex and/or gender in all aspects of cardiovascular research …

The future of heart procurement with donation after circulatory death: current practice and opportunities for advancement

A Ayer, JN Schroder, S Casalinova, JW Doberne… - The Journal of Heart and …, 2022 - Elsevier
Heart Donation after Circulatory Death (DCD) has the potential to significantly increase the
number of patients benefitting from heart transplantation. However, the expansion of DCD …

Multi-indicator analysis of mechanical blood damage with five clinical ventricular assist devices

Y Li, H Wang, Y Xi, A Sun, X Deng, Z Chen… - Computers in biology and …, 2022 - Elsevier
Purpose Device-induced blood damage contributes the hemolysis, thrombosis and bleeding
complications in patients supported with ventricular assist device (VAD). This study aims to …

[HTML][HTML] Heart transplantation from donation after circulatory death: Impact on waitlist time and transplant rate

YK Gernhofer, QM Bui, JJ Powell, PM Perez… - American Journal of …, 2023 - Elsevier
The effect of using donation after circulatory death (DCD) hearts on waitlist outcomes has
not been substantiated. We retrospectively analyzed 184 heart transplant (HT) candidates at …

[HTML][HTML] A new way to evaluate thrombotic risk in failure heart and ventricular assist devices

Y Li, Y Xi, H Wang, A Sun, X Deng, Z Chen… - Medicine in Novel …, 2022 - Elsevier
Thrombosis is one of the main complications in patients implanted with ventricular assist
device (VAD). The complicated structure and disturbed flow field within failure heart and …

[HTML][HTML] Hypothermic, oxygenated perfusion (HOPE) provides cardioprotection via succinate oxidation prior to normothermic perfusion in a rat model of donation after …

RK Wyss, NM Carmona, M Arnold, A Segiser… - American Journal of …, 2021 - Elsevier
In donation after circulatory death (DCD), cardiac grafts are subjected to warm ischemia in
situ, prior to a brief period of cold, static storage (CSS) at procurement, and ex situ …

Improved outcomes in severe primary graft dysfunction after heart transplantation following donation after circulatory death compared with donation after brain death

A Ayer, LK Truby, JN Schroder, S Casalinova… - Journal of Cardiac …, 2023 - Elsevier
Background Primary graft dysfunction (PGD), the leading cause of early mortality after heart
transplantation, is more common following donation after circulatory death (DCD) than …

Normothermic Ex Vivo Heart Perfusion with Mesenchymal Stem Cell‐Derived Conditioned Medium Improves Myocardial Tissue Protection in Rat Donation after …

Z Zeng, L Xu, Y Xu, Y Ruan, D Liu, J Li… - Stem Cells …, 2022 - Wiley Online Library
Objective. Adopting hearts from donation after circulatory death (DCD) is a promising
approach to enlarge the donor pool. Nevertheless, DCD hearts experience severe warm …

Heart donation from donors after controlled circulatory death

L Anguela-Calvet, G Moreno-Gonzalez, F Sbraga… - …, 2021 - journals.lww.com
The gold-standard therapy for advanced-stage heart failure is cardiac transplantation. Since
the first heart transplant in 1967, the majority of hearts transplanted came from brain death …

Anesthetic considerations during heart transplantation using donation after circulatory death

J Ngai, K Masuno, N Moazami - Journal of Cardiothoracic and Vascular …, 2020 - Elsevier
Worldwide, the majority of heart transplant organs are from donation after brain death.
However, the shortage of suitable donors places severe limitations on this route. One option …