Ageing is a crucial risk factor for Alzheimer's disease (AD) and is characterised by systemic
changes in both intracellular and extracellular microenvironments that affect the entire body …

Recent technological developments in spatial transcriptomics allow researchers to measure
gene expression of cells and their spatial locations at the single-cell level, generating …

Spatial transcriptomics (ST) is a newly emerging field that integrates high-resolution imaging
and transcriptomic data to enable the high-throughput analysis of the spatial localization of …

The development of spatial transcriptome sequencing technology has revolutionized our
comprehension of complex tissues and propelled life and health sciences into an era of …

Single-cell RNA sequencing (scRNA-seq) provides insights into gene expression
heterogeneities in diverse cell types underlying homeostasis, development and pathological …

Advances in sequencing and imaging technologies offer a unique opportunity to unravel cell
heterogeneity and develop new immunotherapy strategies for cancer research. There is an …

The tumor microenvironment (TME) represents a complex network in which tumor cells
communicate not only with each other but also with stromal and immune cells. The …

The interactions between tumor cells and the microenvironment play pivotal roles in the
initiation, progression and metastasis of cancer. The advent of spatial transcriptomics data …

The nervous system is one of the most complicated and enigmatic systems within the animal
kingdom. Recently, the emergence and development of spatial transcriptomics (ST) and …

Spatial transcriptomics is an emerging technology to profile spatially resolved gene
expression. Its preserved capture locations allow researchers to investigate transcriptomes …