OBJECTIVES: Heart failure (HF) is defined as the incapability of the heart to serve the
tissues adequately with blood. This includes changes in microvascular perfusion. A …

Astragaloside IV (AS-IV) has been used to treat cardiovascular disease. However, whether
AS-IV exerts a protective effect against hypertensive heart disease has not been …

Objective Sustained β-adrenergic stimulation is a hallmark of sympathetic hyperactivity in
cardiovascular diseases. It is associated with oxidative stress and altered vasoconstrictor …

Background: The understanding of obsesity-related vascular dysfunction remains
controversial mainly because of the diseases associated with vascular injury. Exercise …

Angiotensin-converting enzyme-1 (ACE1) and apolipoproteins (APOs) may play important
roles in the development of Alzheimer's disease (AD) and cardiovascular diseases (CVDs) …

Remote ischemic preconditioning (RIPre) can prevent myocardial injury. The purpose of this
study was to assess the beneficial effects of long-term regular RIPre on human arteries …

Background and Purpose Eugenol, a vanilloid molecule found in some dietary plants,
relaxes vasculature in part via an endothelium‐dependent process; however, the …

AIMS: To determine whether exendin-4 might directly improve endothelial dysfunction in
aorta isolated from high-fat diet-induced obese rats. METHODS: Wistar rats were randomly …

“Fetal Origins of Adult Diseases”(FOAD) or “Barker hypothesis,” also known as the
developmental origins of health and diseases (DoHaD), was initially proposed by David …

The essential role of the endothelium in vascular homeostasis is associated with the release
of endothelium-dependent relaxing and contractile factors (EDRF and EDCF, respectively) …