Background Implanted spinal neuromodulation (SNMD) techniques are used in the
treatment of refractory chronic pain. They involve the implantation of electrodes around the …

Single-cell RNA sequencing (scRNA-seq) has allowed profiling cell types of the dorsal root
ganglia (DRG) and their transcriptional states in physiology and chronic pain. However, the …

Results Several reported cases and a small number of randomized trials were published in
recent years, describing different methods of DRG stimulation and neuromodulation with …

Adeno-associated virus (AAV)-induced dorsal root ganglia (DRG) toxicity has been
observed in several nonclinical species, where lesions are characterized by neuronal …

Pain is a major and common symptom reported as a top priority in patients with rheumatoid
arthritis (RA). Intuitively, RA-related pain is often considered to be a natural consequence of …

Pain is a distressing experience associated with tissue damage or potential tissue damage,
and its occurrence is related to sensory, emotional, cognitive and social factors …

Previous studies on the mechanisms of peripheral nerve injury (PNI) have mainly focused
on the pathophysiological changes within a single injury site. However, recent studies have …

This perspective article focuses on dorsal root ganglia (DRG) as potential fibromyalgia main
pain source. Humans possess 31 pairs of DRG lying along the spine. These ganglia have …

Dorsal root ganglion stimulation (DRG-S) is a form of selective neuromodulation therapy that
targets the dorsal root ganglion. DRG-S offers analgesia in a variety of chronic pain …

Background Dorsal root ganglion stimulation (DRG-S) involves the electrical modulation of
the somata of afferent neural fibers to treat chronic pain. DRG-S has demonstrated clinical …