Lipoprotein (a) in atherosclerotic diseases: from pathophysiology to diagnosis and treatment
Lipoprotein (a)(Lp (a)) is a low-density lipoprotein (LDL) cholesterol-like particle bound to
apolipoprotein (a). Increased Lp (a) levels are an independent, heritable causal risk factor …
apolipoprotein (a). Increased Lp (a) levels are an independent, heritable causal risk factor …
[HTML][HTML] Daring to dream: Targeting lipoprotein (a) as a causal and risk-enhancing factor
ML Koschinsky, ESG Stroes, F Kronenberg - Pharmacological Research, 2023 - Elsevier
Abstract Lipoprotein (a)[Lp (a)], a distinct lipoprotein class, has become a major focus for
cardiovascular research. This review is written in light of the recent guideline and consensus …
cardiovascular research. This review is written in light of the recent guideline and consensus …
Lipoprotein (a) in youth and prediction of major cardiovascular outcomes in adulthood
O Raitakari, N Kartiosuo, K Pahkala, N Hutri-Kähönen… - Circulation, 2023 - Am Heart Assoc
Background: Elevated lipoprotein (a)[Lp (a)] is a common risk factor for cardiovascular
disease outcomes with unknown mechanisms. We examined its potential role in identifying …
disease outcomes with unknown mechanisms. We examined its potential role in identifying …
Lipoprotein (a) and cardiovascular disease in Chinese population: a Beijing heart society expert scientific statement
JJ Li, CS Ma, D Zhao, XW Yan - JACC: Asia, 2022 - jacc.org
Elevated concentration of lipoprotein (a)[Lp (a)] is an independent risk factor for
atherosclerotic cardiovascular disease, including coronary artery disease, stroke, peripheral …
atherosclerotic cardiovascular disease, including coronary artery disease, stroke, peripheral …
The role of high-density lipoprotein cholesterol in 2022
CR Sirtori, A Corsini, M Ruscica - Current atherosclerosis reports, 2022 - Springer
Abstract Purpose of the Review High-density lipoproteins (HDL) are responsible for the
transport in plasma of a large fraction of circulating lipids, in part from tissue mobilization …
transport in plasma of a large fraction of circulating lipids, in part from tissue mobilization …
Omega-3 and cardiovascular prevention–Is this still a choice?
There is currently growing attention being paid to the role of elevated triglycerides (TGs) as
important mediators of residual atherosclerotic cardiovascular disease (ASCVD) risk. This …
important mediators of residual atherosclerotic cardiovascular disease (ASCVD) risk. This …
[PDF][PDF] Low lipoprotein (a) levels predict hepatic fibrosis in patients with nonalcoholic fatty liver disease
Dyslipidemia and cardiovascular complications are comorbidities of nonalcoholic fatty liver
disease (NAFLD), which ranges from simple steatosis to nonalcoholic steatohepatitis …
disease (NAFLD), which ranges from simple steatosis to nonalcoholic steatohepatitis …
RNA-based therapy in the management of lipid disorders: a review
DJ Blom, AD Marais, R Moodley… - Lipids in Health and …, 2022 - Springer
This review focuses on antisense oligonucleotides and small interfering ribonucleic acid
therapies approved or under development for the management of lipid disorders. Recent …
therapies approved or under development for the management of lipid disorders. Recent …
Updates in small interfering RNA for the treatment of dyslipidemias
S Carugo, CR Sirtori, G Gelpi, A Corsini… - Current Atherosclerosis …, 2023 - Springer
Abstract Purpose of Review Atherosclerotic cardiovascular disease (ASCVD) is still the
leading cause of death worldwide. Despite excellent pharmacological approaches, clinical …
leading cause of death worldwide. Despite excellent pharmacological approaches, clinical …
Low-density lipoprotein cholesterol-lowering drugs: a narrative review
N Ferri, M Ruscica, S Fazio, A Corsini - Journal of Clinical Medicine, 2024 - mdpi.com
The modern history of cholesterol-lowering drugs started in 1972 when Dr. Akira Endo
identified an active compound (compactin) that inhibited cholesterol biosynthesis from the …
identified an active compound (compactin) that inhibited cholesterol biosynthesis from the …