Background Nicotinamide adenine dinucleotide (NAD+) metabolism is involved in the entire
physiopathological process and is critical to human health. Long-term imbalance in NAD+ …

Metabolic reactions within cells occur in various isolated compartments with or without
borders, the latter being known as membrane-less organelles (MLOs). The MLOs show …

The current synthetic plastic-based packaging creates environmental hazards that impact
climate change. Hence, the topic of the current research in food packaging is biodegradable …

Myocardial infarction (MI) is a major cause of mortality and disability globally. MI results from
acute or chronic myocardial ischemia characterized by an imbalance of oxygen demand and …

Shikonin and its derivatives are the natural naphthoquinone compounds produced in the
roots of the Boraginaceae family. These red pigments have been used for a long time in …

(1) Background: Shikonin, the main ingredient in Chinese herbal medicine, is described as a
novel angiogenesis inhibitor, and its anticancer effects have already been studied. Shikonin …

Osteoclasts are primary bone-resorbing cells, and receptor-activated NF-kB ligand (RANKL)
stimulation is the key driver of osteoclast differentiation. During late-stage differentiation …

Currently, skin injuries have a serious impact on people's lives and socio-economic stress.
Shikonin, a naphthoquinone compound derived from the root of the traditional Chinese …

Shikonin and its enantiomer, alkannin, are bioactive naphthoquinones produced in several
plants of the family Boraginaceae. The structures of these acylated derivatives, which have …

The quality of Chinese herbal medicine (CHM) directly impacts clinical efficacy and safety.
Fingerprint technology is an internationally recognized method for evaluating the quality of …