[HTML][HTML] Mechanistic role of HPV-associated early proteins in cervical cancer: Molecular pathways and targeted therapeutic strategies
Purpose Cervical cancer (CC), one of the major causes of death of women throughout the
world is primarily caused due to Human Papilloma Virus (HPV) 16 and 18. The early region …
world is primarily caused due to Human Papilloma Virus (HPV) 16 and 18. The early region …
The precision prevention and therapy of HPV‐related cervical cancer: new concepts and clinical implications
Z Hu, D Ma - Cancer medicine, 2018 - Wiley Online Library
Cervical cancer is the third most common cancer in women worldwide, with concepts and
knowledge about its prevention and treatment evolving rapidly. Human papillomavirus …
knowledge about its prevention and treatment evolving rapidly. Human papillomavirus …
[HTML][HTML] Human papillomavirus-related oropharyngeal cancer
High-risk human papillomavirus (HPV) is now recognised as the principal cause of the
increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in some …
increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in some …
[HTML][HTML] Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer
L Zhou, Q Qiu, Q Zhou, J Li, M Yu, K Li, L Xu… - Nature …, 2022 - nature.com
Integration of human papillomavirus (HPV) DNA into the human genome is considered as a
key event in cervical carcinogenesis. Here, we perform comprehensive characterization of …
key event in cervical carcinogenesis. Here, we perform comprehensive characterization of …
[HTML][HTML] The role of integration in oncogenic progression of HPV-associated cancers
AA McBride, A Warburton - PLoS pathogens, 2017 - journals.plos.org
Persistent infection with a subset of “high oncogenic risk” human papillomaviruses (HPVs)
can promote the development of cancer. In these cancers, the extrachromosomal viral …
can promote the development of cancer. In these cancers, the extrachromosomal viral …
Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma
Head and neck squamous cell carcinoma (HNSCC) includes a subset of cancers driven by
human papillomavirus (HPV). Here we use single-cell RNA-seq to profile both HPV-positive …
human papillomavirus (HPV). Here we use single-cell RNA-seq to profile both HPV-positive …
Human papillomavirus molecular biology
Human papillomaviruses are small DNA viruses with a tropism for squamous epithelia. A
unique aspect of human papillomavirus molecular biology involves dependence on the …
unique aspect of human papillomavirus molecular biology involves dependence on the …
Characterization of HPV and host genome interactions in primary head and neck cancers
M Parfenov, CS Pedamallu… - Proceedings of the …, 2014 - National Acad Sciences
Previous studies have established that a subset of head and neck tumors contains human
papillomavirus (HPV) sequences and that HPV-driven head and neck cancers display …
papillomavirus (HPV) sequences and that HPV-driven head and neck cancers display …
[HTML][HTML] The human papillomavirus (HPV)-related cancer biology: An overview
Despite the novel diagnostic methods and therapies implemented in oncology, the number
of patients that succumb by the cancer remains high globally. Currently studies point out that …
of patients that succumb by the cancer remains high globally. Currently studies point out that …
Clinical implications of (epi) genetic changes in HPV-induced cervical precancerous lesions
RDM Steenbergen, PJF Snijders… - Nature Reviews …, 2014 - nature.com
Infection of cervical epithelium with high-risk human papilloma virus (hrHPV) might result in
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …