From pre-diabetes to diabetes: diagnosis, treatments and translational research

RMM Khan, ZJY Chua, JC Tan, Y Yang, Z Liao, Y Zhao - Medicina, 2019 - mdpi.com
Diabetes, a silent killer, is one of the most widely prevalent conditions of the present time.
According to the 2017 International Diabetes Federation (IDF) statistics, the global …

Diabetes and sarcopenic obesity: pathogenesis, diagnosis, and treatments

M Wang, Y Tan, Y Shi, X Wang, Z Liao… - Frontiers in …, 2020 - frontiersin.org
Sarcopenic obesity and diabetes are two increasing health problems worldwide, which both
share many common risk factors, such as aging, and general obesity. The pathogenesis of …

Molecular mechanisms of inflammation in sarcopenia: diagnosis and therapeutic update

GE Jimenez-Gutierrez, LE Martínez-Gómez… - Cells, 2022 - mdpi.com
Sarcopenia is generally an age-related condition that directly impacts the quality of life. It is
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …

PPAR-γ modulators as current and potential cancer treatments

T Chi, M Wang, X Wang, K Yang, F Xie, Z Liao… - Frontiers in …, 2021 - frontiersin.org
Worldwide, cancer has become one of the leading causes of mortality. Peroxisome
Proliferator-Activated Receptors (PPARs) is a family of critical sensors of lipids as well as …

PPAR-α modulators as current and potential cancer treatments

Y Tan, M Wang, K Yang, T Chi, Z Liao, P Wei - Frontiers in oncology, 2021 - frontiersin.org
Cancer is one of the leading causes of mortality worldwide. PPAR modulators may hold
great potential for the management of cancer patients. Indeed, PPARs are critical sensors …

[HTML][HTML] Diabetes and cancer: Epidemiological and biological links

M Wang, Y Yang, Z Liao - World journal of diabetes, 2020 - ncbi.nlm.nih.gov
The incidence of diabetes and cancer has increased significantly in recent years.
Furthermore, there are many common risk factors for both diabetes and cancer, such as …

PPARs and microbiota in skeletal muscle health and wasting

R Manickam, K Duszka, W Wahli - International journal of molecular …, 2020 - mdpi.com
Skeletal muscle is a major metabolic organ that uses mostly glucose and lipids for energy
production and has the capacity to remodel itself in response to exercise and fasting …

Mechanism of traditional Chinese medicine in treating knee osteoarthritis

M Wang, L Liu, CS Zhang, Z Liao, X Jing… - Journal of pain …, 2020 - Taylor & Francis
Knee osteoarthritis (KOA) is a degenerative disease, making a unique contribution to
chronic pain, edema, and limited mobility of knee joint. Traditional Chinese Medicine (TCM) …

Tissue-engineered skeletal muscle models to study muscle function, plasticity, and disease

A Khodabukus - Frontiers in Physiology, 2021 - frontiersin.org
Skeletal muscle possesses remarkable plasticity that permits functional adaptations to a
wide range of signals such as motor input, exercise, and disease. Small animal models have …

Non-coding RNA as biomarkers for type 2 diabetes development and clinical management

T Chi, J Lin, M Wang, Y Zhao, Z Liao… - Frontiers in …, 2021 - frontiersin.org
Diabetes, a metabolic disease characterized by high blood glucose and other complications,
has undefined causes and multiple risk factors, including inappropriate diet, unhealthy …