Molecular basis of atrial fibrillation pathophysiology and therapy: a translational perspective
Atrial fibrillation (AF) is a highly prevalent arrhythmia, with substantial associated morbidity
and mortality. There have been significant management advances over the past 2 decades …
and mortality. There have been significant management advances over the past 2 decades …
Postoperative atrial fibrillation: mechanisms, manifestations and management
Postoperative atrial fibrillation (POAF) complicates 20–40% of cardiac surgical procedures
and 10–20% of non-cardiac thoracic operations. Typical features include onset at 2–4 days …
and 10–20% of non-cardiac thoracic operations. Typical features include onset at 2–4 days …
[HTML][HTML] Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology
Inflammation has been implicated in atrial fibrillation (AF), a very common and clinically
significant cardiac rhythm disturbance, but its precise role remains poorly understood. Work …
significant cardiac rhythm disturbance, but its precise role remains poorly understood. Work …
Computational models of atrial fibrillation: Achievements, challenges, and perspectives for improving clinical care
Despite significant advances in its detection, understanding and management, atrial
fibrillation (AF) remains a highly prevalent cardiac arrhythmia with a major impact on …
fibrillation (AF) remains a highly prevalent cardiac arrhythmia with a major impact on …
Prevention of Pathological Atrial Remodeling and Atrial Fibrillation: JACC State-of-the-Art Review
YC Chen, A Voskoboinik, AL Gerche… - Journal of the American …, 2021 - jacc.org
Atrial enlargement in response to pathological stimuli (eg, hypertension, mitral valve
disease) and physiological stimuli (exercise, pregnancy) can be comparable in magnitude …
disease) and physiological stimuli (exercise, pregnancy) can be comparable in magnitude …
Inflammasome Signaling in Atrial Fibrillation: JACC State-of-the-Art Review
As the most prevalent form of arrhythmia, atrial fibrillation (AF) increases the risk of heart
failure, thromboembolism, and stroke, contributing to the raising mortality and morbidity in …
failure, thromboembolism, and stroke, contributing to the raising mortality and morbidity in …
Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia
LM Moreira, A Takawale, M Hulsurkar, DA Menassa… - Nature, 2020 - nature.com
Atrial fibrillation, the most common cardiac arrhythmia, is an important contributor to mortality
and morbidity, and particularly to the risk of stroke in humans. Atrial-tissue fibrosis is a …
and morbidity, and particularly to the risk of stroke in humans. Atrial-tissue fibrosis is a …
[HTML][HTML] The association between diabetes mellitus and atrial fibrillation: clinical and mechanistic insights
A number of clinical studies have reported that diabetes mellitus (DM) is an independent risk
factor for Atrial fibrillation (AF). After adjustment for other known risk factors including age …
factor for Atrial fibrillation (AF). After adjustment for other known risk factors including age …
Dynamics of atrial fibrillation mechanisms and comorbidities
Atrial fibrillation (AF) contributes to morbidity and mortality of millions of individuals. Its
molecular, cellular, neurohumoral, and hemodynamic pathophysiological mechanisms are …
molecular, cellular, neurohumoral, and hemodynamic pathophysiological mechanisms are …
Inflammasomes and proteostasis novel molecular mechanisms associated with atrial fibrillation
N Li, BJJM Brundel - Circulation research, 2020 - Am Heart Assoc
Atrial fibrillation (AF), the most common progressive and age-related cardiac arrhythmia,
affects millions of people worldwide. AF is associated with common risk factors, including …
affects millions of people worldwide. AF is associated with common risk factors, including …