The neuroscience of drug reward and addiction
ND Volkow, M Michaelides, R Baler - Physiological reviews, 2019 - journals.physiology.org
Drug consumption is driven by a drug's pharmacological effects, which are experienced as
rewarding, and is influenced by genetic, developmental, and psychosocial factors that …
rewarding, and is influenced by genetic, developmental, and psychosocial factors that …
Fractionating impulsivity: neuropsychiatric implications
JW Dalley, TW Robbins - Nature Reviews Neuroscience, 2017 - nature.com
The ability to make decisions and act quickly without hesitation can be advantageous in
many settings. However, when persistently expressed, impulsive decisions and actions are …
many settings. However, when persistently expressed, impulsive decisions and actions are …
[HTML][HTML] Beyond stereotypes of adolescent risk taking: Placing the adolescent brain in developmental context
Recent neuroscience models of adolescent brain development attribute the morbidity and
mortality of this period to structural and functional imbalances between more fully developed …
mortality of this period to structural and functional imbalances between more fully developed …
The nucleus accumbens: mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis
The nucleus accumbens is a major input structure of the basal ganglia and integrates
information from cortical and limbic structures to mediate goal-directed behaviors. Chronic …
information from cortical and limbic structures to mediate goal-directed behaviors. Chronic …
Dissecting impulsivity and its relationships to drug addictions
JD Jentsch, JR Ashenhurst… - Annals of the New …, 2014 - Wiley Online Library
Addictions are often characterized as forms of impulsive behavior. That said, it is often noted
that impulsivity is a multidimensional construct, spanning several psychological domains …
that impulsivity is a multidimensional construct, spanning several psychological domains …
Impulsivity as a vulnerability factor for poor addiction treatment outcomes: a review of neurocognitive findings among individuals with substance use disorders
L Stevens, A Verdejo-García, AE Goudriaan… - Journal of substance …, 2014 - Elsevier
With the current review, we explore the hypothesis that individual differences in
neurocognitive aspects of impulsivity (ie, cognitive and motor disinhibition, delay discounting …
neurocognitive aspects of impulsivity (ie, cognitive and motor disinhibition, delay discounting …
Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence
A growing body of preclinical evidence indicates that addiction to cocaine is associated with
neuroadaptive changes in frontostriatal brain systems. Human studies in cocaine-dependent …
neuroadaptive changes in frontostriatal brain systems. Human studies in cocaine-dependent …
A behavioral and cognitive neuroscience perspective on impulsivity, suicide, and non-suicidal self-injury: Meta-analysis and recommendations for future research
We conducted a meta-analysis of neurobehavioral and neurocognitive indices of impulsivity
in relation to suicidal thoughts and behaviors, as well as non-suicidal self-injury (NSSI). In …
in relation to suicidal thoughts and behaviors, as well as non-suicidal self-injury (NSSI). In …
Genome-wide association studies of impulsive personality traits (BIS-11 and UPPS-P) and drug experimentation in up to 22,861 adult research participants identify …
S Sanchez-Roige, P Fontanillas, SL Elson… - Journal of …, 2019 - Soc Neuroscience
Impulsive personality traits are complex heritable traits that are governed by frontal-
subcortical circuits and are associated with numerous neuropsychiatric disorders …
subcortical circuits and are associated with numerous neuropsychiatric disorders …
Impulsive action and impulsive choice across substance and behavioral addictions: cause or consequence?
JE Grant, SR Chamberlain - Addictive behaviors, 2014 - Elsevier
Substance use disorders are prevalent and debilitating. Certain behavioral syndromes
('behavioral addictions') characterized by repetitive habits, such as gambling disorder …
('behavioral addictions') characterized by repetitive habits, such as gambling disorder …