Human umbilical cord mesenchymal stem cells ameliorate erectile dysfunction in rats with diabetes mellitus through the attenuation of ferroptosis

H Feng, Q Liu, Z Deng, H Li, H Zhang, J Song… - Stem Cell Research & …, 2022 - Springer
Background Erectile dysfunction (ED), as one of the most prevalent consequences in male
diabetic patients, has a serious impact on men's physical and mental health, and the …

Combining transcriptomic analysis and network pharmacology to explore the mechanism by which Shaofu Zhuyu decoction improves diabetes mellitus erectile …

Y Mao, J Sun, Z Wang, Y Liu, J Sun, Z Wei, M Wang… - Phytomedicine, 2023 - Elsevier
Background Erectile dysfunction is common among the complications of diabetes mellitus.
Shaofu Zhuyu decoction (SFZYD) is commonly used to treat diabetic mellitus erectile …

Berberine ameliorates erectile dysfunction in rats with streptozotocin‐induced diabetes mellitus through the attenuation of apoptosis by inhibiting the SPHK1/S1P …

K Liu, T Sun, Y Luan, Y Chen, J Song, L Ling… - …, 2022 - Wiley Online Library
Background The population with diabetes mellitus‐induced erectile dysfunction is
increasing rapidly, but current drugs are not effective in treating erectile dysfunction. Studies …

Uncovering the mechanisms of leech and centipede granules in the treatment of diabetes mellitus-induced erectile dysfunction utilising network pharmacology

JX Ma, B Wang, HS Li, J Yu, HM Hu, CF Ding… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Diabetes mellitus-induced erectile dysfunction (DMED) is
one of the most common complications of diabetes mellitus. Leech and centipede granules …

Paeonol ameliorates diabetic erectile dysfunction by inhibiting HMGB1/RAGE/NF‐kB pathway

T Sun, W Xu, J Wang, J Song, T Wang, S Wang… - …, 2023 - Wiley Online Library
Background The management of diabetes mellitus‐induced erectile dysfunction (DMED) is
progressively becoming tricky due to the surge in the number of patients and the poor …

Translocator protein alleviates allodynia and improves Schwann cell function against diabetic peripheral neuropathy via activation of the Nrf2‐dependent antioxidant …

N Gao, B Ma, H Jia, C Hao, T Jin, X Liu - Diabetic Medicine, 2023 - Wiley Online Library
Aims In diabetes, autophagy and the nuclear factor erythroid‐derived‐2‐like 2 (Nrf2)‐
dependent antioxidant system are impaired. Translocator protein (TSPO) agonist Ro5‐4864 …

Overexpression of PRDX2 in Adipose‐Derived Mesenchymal Stem Cells Enhances the Therapeutic Effect in a Neurogenic Erectile Dysfunction Rat Model by …

P Chen, Z Chen, J Zhai, W Yang… - Oxidative Medicine and …, 2023 - Wiley Online Library
Neurogenic erectile dysfunction (NED) is a common and serious complication after pelvic
surgery. The clinical translation of adipose‐derived mesenchymal stem cell (ADSC) …

Saxagliptin alleviates erectile dysfunction through increasing stromal cell‐derived factor‐1 in diabetes mellitus

T Sun, W Xu, J Wang, T Wang, S Wang, K Liu… - Andrology, 2023 - Wiley Online Library
Background Diabetes mellitus‐induced erectile dysfunction (DMED) is one of the
complications of diabetes and has a poor response to phosphodiesterase type 5 inhibitor …

[HTML][HTML] Fermented Gynochthodes officinalis (FC How) Razafim. & B. Bremer alleviates diabetic erectile dysfunction by attenuating oxidative stress and regulating …

S Liu, K Li, Y Zhao, W Wang, J Bao, X Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance As a traditional Chinese medicine, Gynochthodes
officinalis (FC How) Razafim. & B. Bremer (G. officinalis) has been historically as tonics to …

[HTML][HTML] Isorhamnetin improves diabetes-induced erectile dysfunction in rats through activation of the PI3K/AKT/eNOS signaling pathway

Y Mao, Y Zha, Y Zang, Y Gao, J Sun, Y Liu… - Biomedicine & …, 2024 - Elsevier
Erectile dysfunction is a complex and common complication of diabetes mellitus, which lacks
an effective treatment. The repairing role of vascular endothelium is the current research …