Silybum marianum (milk thistle) and its main constituent, silymarin, as a potential therapeutic plant in metabolic syndrome: A review

A Tajmohammadi, BM Razavi… - Phytotherapy …, 2018 - Wiley Online Library
Metabolic syndrome describes a complex metabolic risk factors including obesity,
hypertension, dyslipidemia, and diabetes. This syndrome is diagnosed by medical …

[HTML][HTML] Silymarin is an ally against insulin resistance: A review

K MacDonald-Ramos, L Michán, A Martínez-Ibarra… - Annals of hepatology, 2021 - Elsevier
Silymarin is obtained from the Milk thistle plant Silybum marianum and has been used over
the centuries to treat principally liver disease, although it has also been studied for its …

Natural compounds for counteracting nonalcoholic fatty liver disease (NAFLD): advantages and limitations of the suggested candidates

N Salvoza, PJ Giraudi, C Tiribelli, N Rosso - International Journal of …, 2022 - mdpi.com
The booming prevalence of nonalcoholic fatty liver disease (NAFLD) in adults and children
will threaten the health system in the upcoming years. The “multiple hit” hypothesis is the …

Effects of silymarin on diabetes mellitus complications: a review

AM Stolf, CC Cardoso, A Acco - Phytotherapy research, 2017 - Wiley Online Library
Diabetes mellitus is a common metabolic disorder that is caused by a deficit in the
production of (type 1) or response to (type 2) insulin. Diabetes mellitus is characterized by a …

Bio-actives from natural products with potential cardioprotective properties: isolation, identification, and pharmacological actions of apigenin, quercetin, and silibinin

EM Tomou, P Papakyriakopoulou, H Skaltsa… - Molecules, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.
As a result, pharmaceutical and non-pharmaceutical interventions modifying risk factors for …

A comprehensive review of the cardiovascular protective properties of Silibinin/Silymarin: A new kid on the block

NPE Kadoglou, C Panayiotou, M Vardas, N Balaskas… - Pharmaceuticals, 2022 - mdpi.com
Silibinin/silymarin has been used in herbal medicine for thousands of years and it is well-
known for its hepato-protective properties. The present comprehensive literature review …

Cardiovascular effects of flavonoids

M Sánchez, M Romero… - Current medicinal …, 2019 - ingentaconnect.com
Cardiovascular Disease (CVD) is the major cause of death worldwide, especially in Western
society. Flavonoids are a large group of polyphenolic compounds widely distributed in …

[HTML][HTML] The therapeutic potential of milk thistle in diabetes

CE Kazazis, AA Evangelopoulos, A Kollas… - The review of diabetic …, 2014 - ncbi.nlm.nih.gov
Milk thistle has been known for more than 2.000 years as a herbal remedy for a variety of
disorders. It has mainly been used to treat liver and gallbladder diseases. Silibum …

A descriptive review of the action mechanisms of berberine, quercetin and silymarin on insulin resistance/hyperinsulinemia and cardiovascular prevention

P Bellavite, S Fazio, F Affuso - Molecules, 2023 - mdpi.com
Insulin resistance (IR) and the associated hyperinsulinemia are early pathophysiological
changes which, if not well treated, can lead to type 2 diabetes, endothelial dysfunction and …

Phytobioactive compound-based nanodelivery systems for the treatment of type 2 diabetes mellitus–current status

P Ganesan, P Arulselvan, DK Choi - International journal of …, 2017 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) is a major chronic disease that is prevalent worldwide, and
it is characterized by an increase in blood glucose, disturbances in the metabolism, and …