Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications
Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …
among the most frequent causes of disability and death worldwide. Current treatment …
[HTML][HTML] The role of immune cells in post-stroke angiogenesis and neuronal remodeling: the known and the unknown
Y Ma, S Yang, Q He, D Zhang, J Chang - Frontiers in immunology, 2021 - frontiersin.org
Following a cerebral ischemic event, substantial alterations in both cellular and molecular
activities occur due to ischemia-induced cerebral pathology. Mounting evidence indicates …
activities occur due to ischemia-induced cerebral pathology. Mounting evidence indicates …
[HTML][HTML] Targeting oxidative stress and inflammation to prevent ischemia-reperfusion injury
The cerebral ischemia injury can result in neuronal death and/or functional impairment,
which leads to further damage and dysfunction after recovery of blood supply. Cerebral …
which leads to further damage and dysfunction after recovery of blood supply. Cerebral …
CXCR2 receptor: regulation of expression, signal transduction, and involvement in cancer
J Korbecki, P Kupnicka, M Chlubek, J Gorący… - International Journal of …, 2022 - mdpi.com
Chemokines are a group of about 50 chemotactic cytokines crucial for the migration of
immune system cells and tumor cells, as well as for metastasis. One of the 20 chemokine …
immune system cells and tumor cells, as well as for metastasis. One of the 20 chemokine …
Bioinformatics analysis of prognostic miRNA signature and potential critical genes in colon cancer
W Chen, C Gao, Y Liu, Y Wen, X Hong… - Frontiers in Genetics, 2020 - frontiersin.org
This study aims to lay a foundation for studying the regulation of microRNAs (miRNAs) in
colon cancer by applying bioinformatics methods to identify miRNAs and their potential …
colon cancer by applying bioinformatics methods to identify miRNAs and their potential …
[HTML][HTML] Key phytochemicals and biological functions of chuanxiong rhizoma against ischemic stroke: a network pharmacology and experimental assessment
P Zeng, Y Yi, HF Su, CY Ye, YW Sun… - Frontiers in …, 2021 - frontiersin.org
Presently, the treatment options for ischemic stroke (IS) are limited due to the complicated
pathological process of the disease. Chuanxiong Rhizome (CR), also known as …
pathological process of the disease. Chuanxiong Rhizome (CR), also known as …
[HTML][HTML] NK cells in cerebral ischemia
C Chen, QD Ai, SF Chu, Z Zhang, NH Chen - Biomedicine & …, 2019 - Elsevier
As a vital cell type in immune system and infiltrating cells in ischemic brain, NK cells can
bridge the crosstalk between immune system and nervous system in stroke setting. The …
bridge the crosstalk between immune system and nervous system in stroke setting. The …
IL-8 exacerbates CCl4-induced liver fibrosis in human IL-8-expressing mice via the PI3K/Akt/HIF-1α pathway
Y Ma, Y Bao, L Wu, Y Ke, L Tan, H Ren, J Song… - Molecular …, 2022 - Elsevier
Liver fibrosis is an excessive accumulation of extracellular matrix (ECM) due to chronic liver
injury. In recent years, the mechanism of liver fibrosis has been extensively studied. Hepatic …
injury. In recent years, the mechanism of liver fibrosis has been extensively studied. Hepatic …
Exploring the hub mechanisms of ischemic stroke based on protein-protein interaction networks related to ischemic stroke and inflammatory bowel disease
W Hu, P Li, N Zeng, S Tan - Scientific Reports, 2023 - nature.com
Ischemic stroke is highly concerning because it often leads to severe long-term neurological
disability. Among clinical trials, ischemic stroke and inflammatory bowel disease interactions …
disability. Among clinical trials, ischemic stroke and inflammatory bowel disease interactions …
Current approaches and future perspectives for nanobodies in stroke diagnostic and therapy
L Jank, C Pinto-Espinoza, Y Duan, F Koch-Nolte… - Antibodies, 2019 - mdpi.com
Antibody-based biologics are the corner stone of modern immunomodulatory therapy.
Though highly effective in dampening systemic inflammatory processes, their large size and …
Though highly effective in dampening systemic inflammatory processes, their large size and …