[HTML][HTML] Tryptophan metabolism and gut-brain homeostasis
Tryptophan is an essential amino acid critical for protein synthesis in humans that has
emerged as a key player in the microbiota-gut-brain axis. It is the only precursor for the …
emerged as a key player in the microbiota-gut-brain axis. It is the only precursor for the …
Mechanisms and molecular targets surrounding the potential therapeutic effects of psychedelics
AM Jaster, J González-Maeso - Molecular psychiatry, 2023 - nature.com
Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …
Structural insights into the lipid and ligand regulation of serotonin receptors
Abstract Serotonin, or 5-hydroxytryptamine (5-HT), is an important neurotransmitter, that
activates the largest subtype family of G-protein-coupled receptors. Drugs that target 5 …
activates the largest subtype family of G-protein-coupled receptors. Drugs that target 5 …
[HTML][HTML] The role of serotonin neurotransmission in gastrointestinal tract and pharmacotherapy
T Guzel, D Mirowska-Guzel - Molecules, 2022 - mdpi.com
5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous
system and peripheral structures, acting also as a hormone in platelets. Although its …
system and peripheral structures, acting also as a hormone in platelets. Although its …
[HTML][HTML] The neurobiology of social play behaviour: past, present and future
EJM Achterberg, LJMJ Vanderschuren - Neuroscience & Biobehavioral …, 2023 - Elsevier
Social play behaviour is a highly energetic and rewarding activity that is of great importance
for the development of brain and behaviour. Social play is abundant during the juvenile and …
for the development of brain and behaviour. Social play is abundant during the juvenile and …
Central 5-HT receptors and their function; present and future
T Sharp, NM Barnes - Neuropharmacology, 2020 - Elsevier
Since our review of central 5-HT receptors and their function twenty years ago, no new 5-HT
receptor has been discovered and there is little evidence that this situation will change in the …
receptor has been discovered and there is little evidence that this situation will change in the …
Structural basis of ligand recognition at the human MT1 melatonin receptor
Abstract Melatonin (N-acetyl-5-methoxytryptamine) is a neurohormone that maintains
circadian rhythms by synchronization to environmental cues and is involved in diverse …
circadian rhythms by synchronization to environmental cues and is involved in diverse …
[HTML][HTML] Cardiac roles of serotonin (5-HT) and 5-HT-receptors in health and disease
J Neumann, B Hofmann, S Dhein, U Gergs - International Journal of …, 2023 - mdpi.com
Serotonin acts solely via 5-HT4-receptors to control human cardiac contractile function. The
effects of serotonin via 5-HT4-receptors lead to positive inotropic and chronotropic effects, as …
effects of serotonin via 5-HT4-receptors lead to positive inotropic and chronotropic effects, as …
[HTML][HTML] Rewiring of the serotonin system in major depression
F Vahid-Ansari, PR Albert - Frontiers in psychiatry, 2021 - frontiersin.org
Serotonin is a key neurotransmitter that is implicated in a wide variety of behavioral and
cognitive phenotypes. Originating in the raphe nuclei, 5-HT neurons project widely to …
cognitive phenotypes. Originating in the raphe nuclei, 5-HT neurons project widely to …
[HTML][HTML] Antibiotics, gut microbiota, and irritable bowel syndrome: What are the relations?
Z Mamieva, E Poluektova, V Svistushkin… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder in which recurrent
abdominal pain is associated with defecation or a change in bowel habits (constipation …
abdominal pain is associated with defecation or a change in bowel habits (constipation …