Regulatory role of mesenchymal stem cells on secondary inflammation in spinal cord injury

QM Pang, SY Chen, SP Fu, H Zhou… - Journal of …, 2022 - Taylor & Francis
Spinal cord injury (SCI) is a catastrophic condition with high morbidity and mortality that still
lacks effective therapeutic strategies. It is well known that the most important stage in SCI …

[HTML][HTML] Induced pluripotent stem cell therapies for cervical spinal cord injury

VM Doulames, GW Plant - International journal of molecular sciences, 2016 - mdpi.com
Cervical-level injuries account for the majority of presented spinal cord injuries (SCIs) to
date. Despite the increase in survival rates due to emergency medicine improvements …

Placental mesenchymal stromal cells rescue ambulation in ovine myelomeningocele

A Wang, EG Brown, L Lankford… - Stem cells …, 2015 - academic.oup.com
Myelomeningocele (MMC)—commonly known as spina bifida—is a congenital birth defect
that causes lifelong paralysis, incontinence, musculoskeletal deformities, and severe …

[HTML][HTML] Effect of SDF-1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal …

J Li, W Guo, M Xiong, H Han… - International …, 2015 - spandidos-publications.com
Accumulating evidence has indicated that the stromal cell-derived factor-1 (SDF-1)/CXC
chemokine receptor 4 (CXCR4) axis plays a crucial role in the recruitment of bone marrow …

[HTML][HTML] Injection of bone marrow mesenchymal stem cells by intravenous or intraperitoneal routes is a viable alternative to spinal cord injury treatment in mice

B dos Santos Ramalho, FM de Almeida… - Neural regeneration …, 2018 - journals.lww.com
In spite of advances in surgical care and rehabilitation, the consequences of spinal cord
injury (SCI) are still challenging. Several experimental therapeutic strategies have been …

Glycosaminoglycan functionalization of electrospun scaffolds enhances Schwann cell activity

M Idini, P Wieringa, S Rocchiccioli, G Nieddu… - Acta biomaterialia, 2019 - Elsevier
Nerve fibers of the peripheral nervous system (PNS) have a remarkable ability to regenerate
up to an almost complete recovery of normal function following a crush or a Sunderland …

Mesenchymal stem cells reduce the oxaliplatin-induced sensory neuropathy through the reestablishment of redox homeostasis in the spinal cord

GGL Dos Santos, ALL Oliveira, DS Santos… - Life Sciences, 2021 - Elsevier
Aims The present study was designed to investigate whether the antinociceptive effect of
bone marrow-derived mesenchymal stem/stromal cells (MSC) during oxaliplatin (OXL) …

Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion

P De Berdt, P Bottemanne, J Bianco… - Cellular and Molecular …, 2018 - Springer
Secondary damage following spinal cord injury leads to non-reversible lesions and
hampering of the reparative process. The local production of pro-inflammatory cytokines …

Mesenchymal stem cells of dental origin-their potential for antiinflammatory and regenerative actions in brain and gut damage

A Földes, K Kádár, B Kerémi, K Gyires… - Current …, 2016 - ingentaconnect.com
Alzheimer's disease, Parkinson's disease, traumatic brain and spinal cord injury and
neuroinflammatory multiple sclerosis are diverse disorders of the central nervous system …

Effects and mechanisms of acupuncture combined with mesenchymal stem cell transplantation on neural recovery after spinal cord injury: progress and prospects

H Tang, Y Guo, Y Zhao, S Wang, J Wang, W Li… - Neural …, 2020 - Wiley Online Library
Spinal cord injury (SCI) is a structural event with devastating consequences worldwide. Due
to the limited intrinsic regenerative capacity of the spinal cord in adults, the neural …