Exploiting the Achilles' heel of cancer: disrupting glutamine metabolism for effective cancer treatment

Y Fan, H Xue, Z Li, M Huo, H Gao… - Frontiers in Pharmacology, 2024 - frontiersin.org
Cancer cells have adapted to rapid tumor growth and evade immune attack by
reprogramming their metabolic pathways. Glutamine is an important nitrogen resource for …

[HTML][HTML] Glutamine Metabolism, A Double Agent Combating or Fueling Hepatocellular Carcinoma

R Abou Ziki, S Colnot - JHEP Reports, 2024 - Elsevier
The reprogramming of glutamine metabolism is a key event in cancers in general, and in
hepatocellular carcinoma (HCC) in particular. This reprogramming supplies the tumor with …

Elucidating the role of hepatic enzymes in spontaneous abortion: a Mendelian randomization approach

Y Zhu, Z Li, X Liu, C Wen - Frontiers in Genetics, 2024 - frontiersin.org
Background While the hepatic enzymes Aspartate Aminotransferase (AST) and Alanine
Aminotransferase (ALT) are crucial for liver function, their role in Spontaneous Abortion (SA) …

Application of microbial enzymes in medicine and industry: current status and future perspectives

A Darbandi, Z Elahi, L Dadgar-Zankbar… - Future …, 2024 - Taylor & Francis
Microbes are a major source of enzymes due to their ability to be mass-cultivated and
genetically modified. Compared with plant and animal enzymes, microbial enzymes are …

Inhibitory Effect of L-Methionine on Alternaria alternata Based on Metabolomics Analysis

X Zhu, S Zhang, Y Yu, S Li, C Yang, Y Chang - Journal of Fungi, 2024 - mdpi.com
Alternaria alternata is the main pathogenic fungus of postharvest black spots in fruits and
vegetables. This study aimed to explore the antifungal activity of methionine on A. alternata …

Experts' opinion in medicine 2022

VI Bunik - Frontiers in Medicine, 2023 - frontiersin.org
Introducing personalized therapies requires a better, than implemented currently, coupling
of basic research to medicine. The current topic is dedicated to promote this coupling …