Colorectal cancer (CRC) is one of the most common cancers in men and women worldwide
as well as is the leading cause of death in the western world. Almost a third of the patients …

In proliferating cells and tissues a number of checkpoints (G1/S and G2/M) preceding cell
division (M-phase) require the signal provided by growth factors present in serum. IGFs (I …

In all eutherian mammals, growth of the fetus is dependent upon a functional placenta, but
whether and how the latter adapts to putative fetal signals is currently unknown. Here, we …

Black tea was reported to alter the microbiome populations and metabolites in diet-induced
obese mice and displays properties that prevent obesity, but the underlying mechanism of …

In sheep, nutrition during the prepubertal stage is essential for growth performance and
mammary gland development. However, the potential effects of nutrient restriction in a …

The cation-independent mannose 6-phosphate (M6P)/Insulin-like growth factor-2 receptor
(CI-MPR/IGF2R) is an∼ 300 kDa transmembrane protein responsible for trafficking M6P …

The precise molecular mechanism behind fetal growth restriction (FGR) is still unclear,
although there is a strong connection between placental dysfunction, inadequate …

Cancer is still a serious public issue that humans face. Chemoresistance is one of the most
important reasons for relapse and poor prognosis. The accumulated data support that the …

Background Transcription of the antisense strand of RTL1 produces a sense mRNA that is
targeted for degradation by antisense microRNAs transcribed from the sense strand …

Background Proliferation of embryonic fibroblasts under the same cell culture conditions,
hinny embryonic fibroblasts (HiEFs) was slower than horse embryonic fibroblast (HEFs) …