Abstract Nrf2 (nuclear factor erythroid 2-related factor 2) is a stress-responsive transcription
factor, associated with cellular homeostasis. Under normal conditions Nrf2 is kept in the …

Inflammatory bowel diseases (IBD) are chronic relapsing idiopathic inflammatory conditions
affecting the gastrointestinal tract. They are mainly represented by two forms, ulcerative …

Ulcerative colitis (UC), as a most common inflammatory bowel disease (IBD), has become a
global public health concern. Exploring novel method of treating UC is urgent and …

Ethnopharmacological relevance Ulcerative colitis (UC) is a chronic inflammatory bowel
disease (IBD), that is associated with a significantly increased risk of colon cancer. As a …

Oxidative stress is a major component of cell damage and cell fat, and as such, it occupies a
central position in the pathogenesis of metabolic disease. Nuclear factor-erythroid-derived 2 …

Probiotics have shown good efficacy in the prevention of ulcerative colitis (UC), but the
specific mechanism remains unclear. Therefore, shotgun metagenomic and transcriptome …

Background Acute liver injury (ALI) caused by sepsis is a fearful disease with high mortality
and poor prognosis. This study aimed to explore the roles and mechanism of Maresin 1 …

The transcription factor NRF2 and its endogenous inhibitor KEAP1 play a crucial role in the
maintenance of cellular redox homeostasis by regulating the gene expression of diverse …

Abstract Ethnopharmacological relevance Genus Canna is used in folk medicine as
demulcent, diaphoretic, antipyretic, mild laxative and in gastrointestinal upsets therapy …

Network pharmacology for systematic understanding of Schisandrin B reduces the epithelial
cells injury of colitis through regulating pyroptosis by AMPK/Nrf2/NLRP3 inflammasome - PMC …