Background Recently, the hallmarks of aging were updated to include dysbiosis, disabled
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …

Therapeutic monoclonal antibodies (mAbs) are standard care for many B-cell
haematological cancers. The modes of action for these mAbs include: induction of cancer …

IL-15 belongs to the common gamma chain cytokine family and has pleiotropic
immunological functions. IL-15 is a homeostatic cytokine essential for the development and …

The immune system comprises multiple cell lineages and heterogeneous subsets found in
blood and tissues throughout the body. While human immune responses differ between …

Dementia with Lewy bodies (DLB) is the second most common neurodegenerative cause of
dementia. People with DLB have an inferior prognosis compared to Alzheimer's disease …

Cellular senescence was first defined as replicative senescence after the works of Hayflick.
Later this concept was extended to many other pathways by which senescence is induced …

Background Although the survival outcomes of childhood cancer patients have improved,
childhood cancer survivors suffer from various degrees of immune dysfunction or delayed …

Cellular senescence throws new insights into patient classification and pharmacological
interventions for clinical management of hepatocellular carcinoma - PMC Back to Top Skip to …

Cellular senescence can be defined as a state of stable, terminal cell cycle arrest which is
associated with various macromolecular changes and a hypersecretory, proinflammatory …

T cells are a family of specialised adaptive immune cells which are central to the
identification and elimination of viral infections. The dynamic activity of T cells is …