Moonlighting proteins at the candidal cell surface

D Satala, J Karkowska-Kuleta, A Zelazna… - Microorganisms, 2020 - mdpi.com
The cell wall in Candida albicans is not only a tight protective envelope but also a point of
contact with the human host that provides a dynamic response to the constantly changing …

Implications of Porphyromonas gingivalis peptidyl arginine deiminase and gingipain R in human health and diseases

YC Chow, HC Yam, B Gunasekaran, WY Lai… - Frontiers in Cellular …, 2022 - frontiersin.org
Porphyromonas gingivalis is a major pathogenic bacterium involved in the pathogenesis of
periodontitis. Citrullination has been reported as the underlying mechanism of the …

Gingipain from Porphyromonas gingivalis causes insulin resistance by degrading insulin receptors through direct proteolytic effects

F Liu, B Zhu, Y An, Z Zhou, P Xiong, X Li, Y Mi… - International Journal of …, 2024 - nature.com
Periodontitis is a critical risk factor for the occurrence and development of diabetes.
Porphyromonas gingivalis may participate in insulin resistance (IR) caused by periodontal …

In it together: Candida–bacterial oral biofilms and therapeutic strategies

G Hwang - Environmental microbiology reports, 2022 - Wiley Online Library
Under natural environmental settings or in the human body, the majority of microorganisms
exist in complex polymicrobial biofilms adhered to abiotic and biotic surfaces. These …

Kinins and their receptors in infectious diseases

APA Dagnino, MM Campos, RBM Silva - Pharmaceuticals, 2020 - mdpi.com
Kinins and their receptors have been implicated in a series of pathological alterations,
representing attractive pharmacological targets for several diseases. The present review …

Living together: The role of Candida albicans in the formation of polymicrobial biofilms in the oral cavity

M Rapala‐Kozik, M Surowiec, M Juszczak… - Yeast, 2023 - Wiley Online Library
The oral cavity of humans is colonized by diversity of microbial community, although
dominated by bacteria, it is also constituted by a low number of fungi, often represented by …

The recruitment and activation of plasminogen by bacteria—the involvement in chronic infection development

D Satala, A Bednarek, A Kozik, M Rapala-Kozik… - International Journal of …, 2023 - mdpi.com
The development of infections caused by pathogenic bacteria is largely related to the
specific properties of the bacterial cell surface and extracellular hydrolytic activity …

Association of chronic periodontitis with multiple sclerosis: A systematic review and meta-analysis

A Tsimpiris, I Tsolianos, A Grigoriadis… - Multiple Sclerosis and …, 2023 - Elsevier
Background Chronic periodontitis (CP) is a multifactorial, chronic inflammatory disease of
microbial etiology that manifests as a result of the dysfunction of the immune mechanism …

The Role of Candida albicans Virulence Factors in the Formation of Multispecies Biofilms With Bacterial Periodontal Pathogens

D Satala, M Gonzalez-Gonzalez, M Smolarz… - Frontiers in Cellular …, 2022 - frontiersin.org
Periodontal disease depends on the presence of different microorganisms in the oral cavity
that during the colonization of periodontal tissues form a multispecies biofilm community …

[HTML][HTML] Extracellular vesicle production: A bidirectional effect in the interplay between host and Candida fungi

K Kulig, M Rapala-Kozik, J Karkowska-Kuleta - Current Research in …, 2024 - Elsevier
Candida fungi exploit various virulence strategies to invade the human host, while host cells
employ diverse mechanisms to maintain homeostasis and respond to infection. Extracellular …