Genetics and neurobiology of eating disorders
Eating disorders (anorexia nervosa, bulimia nervosa and binge-eating disorder) are a
heterogeneous class of complex illnesses marked by weight and appetite dysregulation …
heterogeneous class of complex illnesses marked by weight and appetite dysregulation …
[HTML][HTML] Eating disorders, heredity and environmental activation: getting epigenetic concepts into practice
Epigenetic mechanisms are believed to link environmental exposures to alterations in gene
expression, and in so doing, to provide a physical substrate for the activation of hereditary …
expression, and in so doing, to provide a physical substrate for the activation of hereditary …
[HTML][HTML] Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia
A Gialluisi, TFM Andlauer, N Mirza-Schreiber… - Molecular …, 2021 - nature.com
Developmental dyslexia (DD) is a learning disorder affecting the ability to read, with a
heritability of 40–60%. A notable part of this heritability remains unexplained, and large …
heritability of 40–60%. A notable part of this heritability remains unexplained, and large …
Immunoinflammatory processes: Overlapping mechanisms between obesity and eating disorders?
Obesity and eating disorders are conditions that involve eating behaviors and are
sometimes comorbid. Current evidence supports alterations in immunoinflammatory …
sometimes comorbid. Current evidence supports alterations in immunoinflammatory …
Genetic risk factors for eating disorders: an update and insights into pathophysiology
H Himmerich, J Bentley, C Kan… - Therapeutic advances …, 2019 - journals.sagepub.com
Genome-wide-association studies (GWASs), epigenetic, gene-expression and gene–gene
interaction projects, nutritional genomics and investigations of the gut microbiota have …
interaction projects, nutritional genomics and investigations of the gut microbiota have …
[HTML][HTML] What next for eating disorder genetics? Replacing myths with facts to sharpen our understanding
Substantial progress has been made in the understanding of anorexia nervosa (AN) and
eating disorder (ED) genetics through the efforts of large-scale collaborative consortia …
eating disorder (ED) genetics through the efforts of large-scale collaborative consortia …
Genetics of anorexia nervosa
JH Baker, K Schaumberg, MA Munn-Chernoff - Current psychiatry reports, 2017 - Springer
Abstract Purpose of Review Genetic factors contribute to the etiology of anorexia nervosa
(AN). This review synthesizes the current state of knowledge about the genetic etiology of …
(AN). This review synthesizes the current state of knowledge about the genetic etiology of …
[HTML][HTML] Differential methylation patterns in lean and obese non-alcoholic steatohepatitis-associated hepatocellular carcinoma
E Hymel, KW Fisher, PA Farazi - BMC cancer, 2022 - Springer
Background Nonalcoholic fatty liver disease affects about 24% of the world's population and
may progress to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular …
may progress to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular …
[HTML][HTML] SIRT1 accelerates the progression of activity-based anorexia
TM Robinette, JW Nicholatos, AB Francisco… - Nature …, 2020 - nature.com
Food consumption is fundamental for life, and eating disorders often result in devastating or
life-threatening conditions. Anorexia nervosa (AN) is characterized by a persistent restriction …
life-threatening conditions. Anorexia nervosa (AN) is characterized by a persistent restriction …
A metabolic perspective on reward abnormalities in anorexia nervosa
Anorexia nervosa (AN) is the psychiatric disorder with the highest mortality rate; however,
the mechanisms responsible for its pathogenesis remain largely unknown. Large-scale …
the mechanisms responsible for its pathogenesis remain largely unknown. Large-scale …