Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans
DH Yang, KW Jung, S Bang, JW Lee, MH Song… - Genetics, 2017 - academic.oup.com
Thermotolerance is a crucial virulence attribute for human pathogens, including the fungus
Cryptococcus neoformans that causes fatal meningitis in humans. Loss of the protein kinase …
Cryptococcus neoformans that causes fatal meningitis in humans. Loss of the protein kinase …
Evaluation of Mycograb®, amphotericin B, caspofungin, and fluconazole in combination against Cryptococcus neoformans by checkerboard and time-kill …
L Nooney, RC Matthews, JP Burnie - Diagnostic microbiology and infectious …, 2005 - Elsevier
This article reported the identification of heat shock protein 90 (hsp90) homologues by
immunoblot in Cryptococcus neoformans. Mycograb®, a genetically recombinant antibody …
immunoblot in Cryptococcus neoformans. Mycograb®, a genetically recombinant antibody …
A Multi-Host Approach for the Systematic Analysis of Virulence Factors in Cryptococcus neoformans
A Desalermos, X Tan, R Rajamuthiah… - The Journal of …, 2015 - academic.oup.com
A multi-host approach was followed to screen a library of 1201 signature-tagged deletion
strains of Cryptococcus neoformans mutants to identify previously unknown virulence …
strains of Cryptococcus neoformans mutants to identify previously unknown virulence …
Calcium- and Calcineurin-Independent Roles for Calmodulin in Cryptococcus neoformans Morphogenesis and High-Temperature Growth
PR Kraus, CB Nichols, J Heitman - Eukaryotic cell, 2005 - Am Soc Microbiol
The function of calcium as a signaling molecule is conserved in eukaryotes from fungi to
humans. Previous studies have identified the calcium-activated phosphatase calcineurin as …
humans. Previous studies have identified the calcium-activated phosphatase calcineurin as …
Characterization of the Complete Uric Acid Degradation Pathway in the Fungal Pathogen Cryptococcus neoformans
IR Lee, L Yang, G Sebetso, R Allen, THN Doan… - PloS one, 2013 - journals.plos.org
Degradation of purines to uric acid is generally conserved among organisms, however, the
end product of uric acid degradation varies from species to species depending on the …
end product of uric acid degradation varies from species to species depending on the …
Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms
Abstract Streptothricin‐F (STT‐F), one of the early‐discovered antibiotics, consists of three
components, a β‐lysine homopolymer, an aminosugar d‐gulosamine, and an unusual …
components, a β‐lysine homopolymer, an aminosugar d‐gulosamine, and an unusual …
Essential gene discovery in the basidiomycete Cryptococcus neoformans for antifungal drug target prioritization
Fungal diseases represent a major burden to health care globally. As with other pathogenic
microbes, there is a limited number of agents suitable for use in treating fungal diseases …
microbes, there is a limited number of agents suitable for use in treating fungal diseases …
A critical assessment of Agrobacterium tumefaciens-mediated transformation as a tool for pathogenicity gene discovery in the phytopathogenic fungus Leptosphaeria …
F Blaise, E Rémy, M Meyer, L Zhou, JP Narcy… - Fungal Genetics and …, 2007 - Elsevier
We evaluated the usefulness and robustness of Agrobacterium tumefaciens-mediated
transformation (ATMT) as a high-throughput transformation tool for pathogenicity gene …
transformation (ATMT) as a high-throughput transformation tool for pathogenicity gene …
Transcription factor Znf2 coordinates with the chromatin remodeling SWI/SNF complex to regulate cryptococcal cellular differentiation
Cellular differentiation is instructed by developmental regulators in coordination with
chromatin remodeling complexes. Much information about their coordination comes from …
chromatin remodeling complexes. Much information about their coordination comes from …
Ferrochelatase is a conserved downstream target of the blue light-sensing White collar complex in fungi
Light is a universal signal perceived by organisms, including fungi, in which light regulates
common and unique biological processes depending on the species. Previous research has …
common and unique biological processes depending on the species. Previous research has …