Pheromone independent unisexual development in Cryptococcus neoformans

R Gyawali, Y Zhao, J Lin, Y Fan, X Xu… - PLoS …, 2017 - journals.plos.org
The fungus Cryptococcus neoformans can undergo a-α bisexual and unisexual
reproduction. Completion of both sexual reproduction modes requires similar cellular …

Overcoming recalcitrant transformation and gene manipulation in Pucciniomycotina yeasts

EP Abbott, G Ianiri, R Castoria, A Idnurm - Applied microbiology and …, 2013 - Springer
The red yeasts of the Pucciniomycotina have rarely been transformed with DNA molecules.
Transformation methods were recently developed for a species of Sporobolomyces, based …

Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans

SS Giles, JR Perfect, GM Cox - Fungal Genetics and Biology, 2005 - Elsevier
Cryptococcus neoformans is an opportunistic pathogen and the leading cause of fungal
meningitis. To survive within the host, this organism must be able to protect itself from …

Generation of stable mutants and targeted gene deletion strains in Cryptococcus neoformans through electroporation

X Lin, N Chacko, L Wang, Y Pavuluri - Medical mycology, 2015 - academic.oup.com
Cryptococcus neoformans is the etiologic agent of cryptococcal meningitis that causes more
than half a million deaths worldwide each year. This capsulated basidiomycetous yeast also …

Identification of virulence genes in Fusarium oxysporum f. sp. lycopersici by large‐scale transposon tagging

MS LÓPEZ‐BERGES, A Di Pietro… - Molecular Plant …, 2009 - Wiley Online Library
Forward genetic screens are efficient tools for the dissection of complex biological
processes, such as fungal pathogenicity. A transposon tagging system was developed in the …

Cryptotrichosporon anacardii gen. nov., sp. nov., a new trichosporonoid capsulate basidiomycetous yeast from Nigeria that is able to form melanin on niger seed agar

I Okoli, CA Oyeka, KJ Kwon-Chung… - FEMS yeast …, 2007 - academic.oup.com
Five yeast isolates obtained from cashew tree flowers in Nigeria resembled Cryptococcus
neoformans phenotypically by producing brown pigmented colonies on niger seed agar …

The calcium transporter Pmc1 provides Ca2+ tolerance and influences the progression of murine cryptococcal infection

L Kmetzsch, CC Staats, JB Cupertino… - The FEBS …, 2013 - Wiley Online Library
The Ca2+‐calcineurin signaling pathway in the human fungal pathogen Cryptococcus
neoformans is essential for adaptation to the host environment during infection. Calcium …

Cryptococcal phosphoglucose isomerase is required for virulence factor production, cell wall integrity and stress resistance

P Zhang, D Wei, Z Li, Z Sun, J Pan… - FEMS yeast …, 2015 - academic.oup.com
Regulation of virulence factor production in the pathogen Cryptococcus neoformans remains
to be fully illustrated. We present here a finding that a gene, encoding the glycolysis enzyme …

[HTML][HTML] The role of the de novo pyrimidine biosynthetic pathway in Cryptococcus neoformans high temperature growth and virulence

FA de Gontijo, RC Pascon, L Fernandes… - Fungal genetics and …, 2014 - Elsevier
Fungal infections are often difficult to treat due to the inherent similarities between fungal
and animal cells and the resulting host toxicity from many antifungal compounds …

Blastomyces dermatitidis yeast cells inhibit nitric oxide production by alveolar macrophage inducible nitric oxide synthase

NM Rocco, JC Carmen, BS Klein - Infection and immunity, 2011 - Am Soc Microbiol
The ability of pathogens to evade host antimicrobial mechanisms is crucial to their virulence.
The dimorphic fungal pathogen Blastomyces dermatitidis can infect immunocompetent …