Testing the proportional hazards assumption in cox regression and dealing with possible non-proportionality in total joint arthroplasty research: methodological …
Background Survival analysis and effect of covariates on survival time is a central research
interest. Cox proportional hazards regression remains as a gold standard in the survival …
interest. Cox proportional hazards regression remains as a gold standard in the survival …
BNT162b2 vaccine booster and mortality due to Covid-19
Background The emergence of the B. 1.617. 2 (delta) variant of severe acute respiratory
syndrome coronavirus 2 and the reduced effectiveness over time of the BNT162b2 vaccine …
syndrome coronavirus 2 and the reduced effectiveness over time of the BNT162b2 vaccine …
[HTML][HTML] Survival analysis: part II-applied clinical data analysis
J In, DK Lee - Korean J Anesthesiol, 2019 - synapse.koreamed.org
As a follow-up to a previous article, this review provides several in-depth concepts regarding
a survival analysis. Also, several codes for specific survival analysis are listed to enhance …
a survival analysis. Also, several codes for specific survival analysis are listed to enhance …
Metformin is associated with higher incidence of acidosis, but not mortality, in individuals with COVID-19 and pre-existing type 2 diabetes
The safety and efficacy of anti-diabetic drugs are critical for maximizing the beneficial
impacts of well-controlled blood glucose on the prognosis of individuals with COVID-19 and …
impacts of well-controlled blood glucose on the prognosis of individuals with COVID-19 and …
Clinical characteristics and outcomes of critically ill patients with novel coronavirus infectious disease (COVID-19) in China: a retrospective multicenter study
J Xie, W Wu, S Li, Y Hu, M Hu, J Li, Y Yang… - Intensive care …, 2020 - Springer
Purpose An ongoing outbreak of coronavirus disease 2019 (COVID-19) emerged in Wuhan
since December 2019 and spread globally. However, information about critically ill patients …
since December 2019 and spread globally. However, information about critically ill patients …
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS
PJ Hop, RAJ Zwamborn, E Hannon… - Science translational …, 2022 - science.org
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with an estimated
heritability between 40 and 50%. DNA methylation patterns can serve as proxies of (past) …
heritability between 40 and 50%. DNA methylation patterns can serve as proxies of (past) …
Longer-term all-cause and cardiovascular mortality with intensive blood pressure control: a secondary analysis of a randomized clinical trial
Importance The Systolic Blood Pressure Intervention Trial (SPRINT) showed that intensive
blood pressure control reduced cardiovascular morbidity and mortality. However, the legacy …
blood pressure control reduced cardiovascular morbidity and mortality. However, the legacy …
Biological rhythms in COVID-19 vaccine effectiveness in an observational cohort study of 1.5 million patients
BACKGROUND Circadian rhythms are evident in basic immune processes, but it is unclear
if rhythms exist in clinical endpoints like vaccine protection. Here, we examined associations …
if rhythms exist in clinical endpoints like vaccine protection. Here, we examined associations …
Real-time prediction of COVID-19 related mortality using electronic health records
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory disease with rapid human-to-
human transmission caused by the severe acute respiratory syndrome coronavirus 2 (SARS …
human transmission caused by the severe acute respiratory syndrome coronavirus 2 (SARS …
Expression of hub genes of endothelial cells in glioblastoma-A prognostic model for GBM patients integrating single-cell RNA sequencing and bulk RNA sequencing
S Zhao, W Ji, Y Shen, Y Fan, H Huang, J Huang, G Lai… - BMC cancer, 2022 - Springer
Background This study aimed to use single-cell RNA-seq (scRNA-seq) to discover marker
genes in endothelial cells (ECs) and construct a prognostic model for glioblastoma …
genes in endothelial cells (ECs) and construct a prognostic model for glioblastoma …