[HTML][HTML] Radioiodine-refractory thyroid cancer: molecular basis of redifferentiation therapies, management, and novel therapies

M Aashiq, DA Silverman, S Na'ara, H Takahashi… - Cancers, 2019 - mdpi.com
Recurrent, metastatic disease represents the most frequent cause of death for patients with
thyroid cancer, and radioactive iodine (RAI) remains a mainstay of therapy for these patients …

Risk stratification in differentiated thyroid cancer: from detection to final follow-up

RM Tuttle, AS Alzahrani - The Journal of Clinical Endocrinology …, 2019 - academic.oup.com
Context Modern management of differentiated thyroid cancer requires individualized care
plans that tailor the intensity of therapy and follow-up to the estimated risks of recurrence …

Thyroid nodules: diagnostic evaluation based on thyroid cancer risk assessment

NS Ospina, NM Iñiguez-Ariza, MR Castro - bmj, 2020 - bmj.com
Thyroid nodules are extremely common and can be detected by sensitive imaging in more
than 60% of the general population. They are often identified in patients without symptoms …

[HTML][HTML] From biomarkers to therapeutic targets: the promise of PD-L1 in thyroid autoimmunity and cancer

G D'Andréa, S Lassalle, N Guevara, B Mograbi… - Theranostics, 2021 - ncbi.nlm.nih.gov
The programmed cell death-1/programmed cell death ligand-1 (PD-1/PD-L1) immune
checkpoint proteins hold promise as diagnostic, prognostic, and therapeutic targets for …

[HTML][HTML] Increased expression of GPX4 promotes the tumorigenesis of thyroid cancer by inhibiting ferroptosis and predicts poor clinical outcomes

H Chen, F Peng, J Xu, G Wang, Y Zhao - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Background: Ferroptosis plays a critical role in suppressing cancer progression, and its
essential regulator is glutathione peroxidase 4 (GPX4). High GPX4 expression can inhibit …

[HTML][HTML] Long-term outcome of differentiated thyroid cancer patients—Fifty years of Croatian thyroid disease referral centre experience

T Jukić, I Blažeković, M Franceschi, PP Ovčariček… - Diagnostics, 2022 - mdpi.com
Background: Indolent nature but a high incidence of differentiated thyroid cancer (DTC)
remains a challenge for optimizing patient care. Therefore, prognostic factors present …

The Antitumour Effect of Prunella vulgaris Extract on Thyroid Cancer Cells In Vitro and In Vivo

F Yu, L Zhang, R Ma, C Liu, Q Wang… - … and Alternative Medicine, 2021 - Wiley Online Library
Prunella vulgaris, a traditional Chinese medicine, has been used to treat various benign and
malignant tumours for centuries in China. In our previous studies, Prunella vulgaris extract …

Plant natural products with anti-thyroid cancer activity

J Sharifi-Rad, S Rajabi, M Martorell, MD López… - Fitoterapia, 2020 - Elsevier
Thyroid cancer is the most frequent endocrine malignancy, with more than 500,000 cases
per year worldwide. Differentiated thyroid cancers are the most common forms with best …

[HTML][HTML] Androgen activity is associated with PD-L1 downregulation in thyroid cancer

TJ O'Connell, S Dadafarin, M Jones… - Frontiers in Cell and …, 2021 - frontiersin.org
Thyroid cancer is the most prevalent endocrine malignancy in the United States with greater
than 53,000 new cases in 2020. There is a significant gender disparity in disease incidence …

[HTML][HTML] The age threshold of the 8th edition AJCC classification is useful for indicating patients with aggressive papillary thyroid cancer in clinical practice

K Kaliszewski, D Diakowska, Ł Nowak, B Wojtczak… - BMC cancer, 2020 - Springer
Background Papillary thyroid cancer (PTC) is unique among cancers in that patient age is a
consideration in staging. One of the most important modifications in the 8th Edition of the …