Probiotics for neurodegenerative diseases: a systemic review

S Ojha, N Patil, M Jain, C Kole, P Kaushik - Microorganisms, 2023 - mdpi.com
Neurodegenerative disorders (ND) are a group of conditions that affect the neurons in the
brain and spinal cord, leading to their degeneration and eventually causing the loss of …

Towards improved screening of toxins for Parkinson's risk

L Shan, HJ Heusinkveld, KC Paul, S Hughes… - npj Parkinson's …, 2023 - nature.com
Parkinson's disease (PD) is a chronic, progressive and disabling neurodegenerative
disorder. The prevalence of PD has risen considerably over the past decades. A growing …

Roles of α-Synuclein and Disease-Associated Factors in Drosophila Models of Parkinson's Disease

M Suzuki, K Sango, Y Nagai - International Journal of Molecular Sciences, 2022 - mdpi.com
α-Synuclein (αSyn) plays a major role in the pathogenesis of Parkinson's disease (PD),
which is the second most common neurodegenerative disease after Alzheimer's disease …

Drosophila as a toolkit to tackle cancer and its metabolism

H Jiang, T Kimura, H Hai, R Yamamura… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the most severe health problems worldwide accounting for the second
leading cause of death. Studies have indicated that cancers utilize different metabolic …

[HTML][HTML] Progress in Parkinson's disease animal models of genetic defects: Characteristics and application

C Zhang, S Chen, X Li, Q Xu, Y Lin, F Lin… - Biomedicine & …, 2022 - Elsevier
Parkinson's disease (PD) is the second major progressive neurodegenerative disease,
which critically impacts patients' quality of life. Based on genetics, animal models of genetic …

Chronic Exposure to Paraquat Induces Alpha-Synuclein Pathogenic Modifications in Drosophila

JN Arsac, M Sedru, M Dartiguelongue, J Vulin… - International Journal of …, 2021 - mdpi.com
Parkinson's disease (PD) is characterized by the progressive accumulation of neuronal
intracellular aggregates largely composed of alpha-Synuclein (αSyn) protein. The process of …

Exploration of the α-syn/T199678/miR-519–3p/KLF9 pathway in a PD-related α-syn pathology

D Lin, Y Li, K Huang, Y Chen, X Jing, Y Liang, L Bu… - Brain Research …, 2022 - Elsevier
Background Kruppel-like factor 9 (KLF9) plays a key role as an inducer of cellular oxidative
stress in the modulation of cell death and in oxidant-dependent tissue injury. Our previous …

The Discovery of Novel PGK1 Activators as Apoptotic Inhibiting and Neuroprotective Agents

SJ Qiang, YQ Shi, TY Wu, JQ Wang, XL Chen… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second leading cause of death worldwide and the leading cause of long-term
disability that seriously endangers health and quality of human life. Tissue-type fibrinogen …

Narrative review concerning the clinical spectrum of ophthalmological impairments in Parkinson's disease

AZ Stuparu, S Jurja, AF Stuparu, A Axelerad - Neurology International, 2023 - mdpi.com
Ophthalmic non-motor impairments are common in Parkinson's disease patients, from the
onset of the neurodegenerative disease and even prior to the development of motor …

Neuroprotective action of Smilax china ethanolic bark extract in treatment of a prominent aging disorder: Parkinson's disease induced by rotenone

A Sayyaed, N Saraswat, A Kulkarni… - Future Journal of …, 2023 - Springer
Background Tremors, psychological difficulties, mental health issues, depression, impulsive
acts, and other behavioral abnormalities are all symptoms of Parkinson's disease, a …