Budd-Chiari syndrome and non-cirrhotic non-tumoral portal vein thrombosis are 2 rare
disorders, with several similarities that are categorized under the term splanchnic vein …

The liver is not only the largest organ in the body but also the one playing one of the most
important role in the human metabolism as it is in charge of transforming toxic substances in …

Highlights•Model-informed drug discovery and development (MID3) is poised to facilitate a
major evolution in the way drugs R&D is conducted.•Employing computational models aids …

The liver plays a key role in the metabolic homeostasis of the whole organism. To carry out
its functions, it is endowed with a peculiar circulatory system, made of three main dendritic …

Colorectal cancer and other cancers often metastasize to the liver in later stages of the
disease, contributing significantly to patient death. While the biomechanical properties of the …

Two dimensional, steady state, and incompressible blood and bile flows through the liver
lobules are numerically simulated. Two different geometric models A and B are proposed to …

Shear wave elastography (SWE) enables the probing of the mechanical properties of soft
tissues in vivo and has been demonstrated to be a promising technique for the diagnosis of …

In shear wave elastography, rotational wave speeds are converted to elasticity measures
using elastodynamic theory. The method has a wide range of applications and is the gold …

Hepatic physiology depends on the liver's complex structural composition which among
others, provides high oxygen supply rates, locally differential oxygen tension, endothelial …

A convenient geometrical description of the microvascular network is necessary for
computationally efficient mathematical modelling of liver perfusion, metabolic and other …