Simple Summary Natural killer T (NKT) cells are a subset of lipid-reactive T cells that
enhance anti-tumor immunity. While preclinical studies have shown NKT cell …

The treatment outcome of breast cancer is closely related to estrogen receptor (ER),
progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) …

The dynamic composition of the tumor microenvironment (TME) can markedly alter the
response to targeted therapies for colorectal cancer. Cancer-associated fibroblasts (CAF) …

Abstract Background Tumour infiltrating lymphocytes (TILs) are a prognostic parameter in
triple-negative and human epidermal growth factor receptor 2 (HER2)-positive breast cancer …

The metastasis and poor prognosis are still regarded as the main challenge in the clinical
treatment of breast cancer (BC). Both N6-methyladenosine (m6A) modification and lncRNAs …

Simple Summary The roles of “like-Smith”(LSM) proteins in breast cancer development and
their clinical relevance remain unclear. In this study, multiple analyses based on 3593 …

Background and aims CCL5 is considered to contribute to the biological function of a variety
of cancer types, but its specific mechanism is still unclear. This study aimed to reveal the …

Tumor-infiltrating T cells recognize, attack, and clear tumor cells, playing a central role in
antitumor immune response. However, certain immune cells can impair this response and …

Bariatric surgery is a sustainable weight loss approach, including vertical sleeve
gastrectomy (VSG). Obesity exacerbates tumor growth, while diet-induced weight loss …

Cyclic dinucleotides (CDNs) are a promising class of immune agonists that trigger the
stimulator of interferon genes (STING) to activate both innate and acquired immunity …