Comprehensive review of mechanisms of pathogenesis involved in Alzheimer's disease and potential therapeutic strategies
AD is a progressive neurodegenerative disorder and a leading cause of dementia in an
aging population worldwide. The enormous challenge which AD possesses to global …
aging population worldwide. The enormous challenge which AD possesses to global …
Therapies for prevention and treatment of Alzheimer's disease
J Mendiola-Precoma, LC Berumen… - BioMed research …, 2016 - Wiley Online Library
Alzheimer's disease (AD) is the most common cause of dementia associated with a
progressive neurodegenerative disorder, with a prevalence of 44 million people throughout …
progressive neurodegenerative disorder, with a prevalence of 44 million people throughout …
Alzheimer's disease: Molecular aspects and treatment opportunities using herbal drugs
Abstract Alzheimer's disease (AD), also called senile dementia, is the most common
neurological disorder. Around 50 million people, mostly of advanced age, are suffering from …
neurological disorder. Around 50 million people, mostly of advanced age, are suffering from …
Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development
BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …
Structural Modification, In Vitro, In Vivo, Ex Vivo, and In Silico Exploration of Pyrimidine and Pyrrolidine Cores for Targeting Enzymes Associated with …
MA Javed, N Ashraf, M Saeed Jan… - ACS Chemical …, 2021 - ACS Publications
To obtain a multipotent framework that can target simultaneously COX-2, 5-LOX,
acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) to treat neuroinflammation …
acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) to treat neuroinflammation …
Royal jelly as an intelligent anti-aging agent—A focus on cognitive aging and Alzheimer's disease: A review
AM Ali, H Kunugi - Antioxidants, 2020 - mdpi.com
The astronomical increase of the world's aged population is associated with the increased
prevalence of neurodegenerative diseases, heightened disability, and extremely high costs …
prevalence of neurodegenerative diseases, heightened disability, and extremely high costs …
Pivotal role of nitrogen heterocycles in Alzheimer's disease drug discovery
Alzheimer's disease (AD) is a detrimental neurodegenerative disease that progressively
worsens with time. Clinical options are limited and only provide symptomatic relief to AD …
worsens with time. Clinical options are limited and only provide symptomatic relief to AD …
Muscarinic and nicotinic acetylcholine receptor agonists: current scenario in Alzheimer's disease therapy
Objectives Alzheimer's disease (AD) has become the primary cause of dementia. It shows a
progressive cognitive dysfunction with degenerating neurons. Acetylcholine receptors …
progressive cognitive dysfunction with degenerating neurons. Acetylcholine receptors …
Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer's disease: A review
Y Jiang, H Gao, G Turdu - Bioorganic chemistry, 2017 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease affecting 25 million
people worldwide, and cholinergic hypothesis is considered as an important hypotheses in …
people worldwide, and cholinergic hypothesis is considered as an important hypotheses in …
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase
ED AlFadly, PA Elzahhar, A Tramarin, S Elkazaz… - European journal of …, 2019 - Elsevier
Neuroinflammation and cholinergic deficit are key detrimental processes involved in
Alzheimer's disease. Hence, in the search for novel and effective treatment strategies, the …
Alzheimer's disease. Hence, in the search for novel and effective treatment strategies, the …