Heart failure (HF) is a significant cause of morbidity and mortality worldwide. Circulating
biomarkers reflecting pathophysiological pathways involved in HF development and …

Remarkable recent advances have revolutionized the field of heart failure. Survival has
improved among individuals with heart failure and a reduced ejection fraction and for the …

Recent advances indicate that biological aging is a potentially modifiable driver of late-life
function and chronic disease and have led to the development of geroscience-guided …

Heart failure (HF) biomarkers have dramatically impacted the way HF patients are evaluated
and managed. B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) are the …

Background In most patients with stable coronary artery disease, plasma cardiac troponin T
levels are below the limit of detection for the conventional assay. The distribution and …

Dilated cardiomyopathy is characterised by left ventricular dilation that is associated with
systolic dysfunction. Diastolic dysfunction and impaired right ventricular function can …

Heart failure results not only from cardiac overload or injury but also from a complex
interplay among genetic, neurohormonal, inflammatory, and biochemical changes acting on …

Thus, the task of writing Guidelines or Expert Consensus Documents covers not only the
integration of the most recent research, but also the creation of educational tools and …

Recently, the 4th Universal Definition of Myocardial Infarction was published. 1 Perhaps it is
time to consider a First Universal Definition of Heart Failure. Objective, clinically verifiable …

Background—The role of mitral valve repair (MVR) during coronary artery bypass grafting
(CABG) in patients with moderate ischemic mitral regurgitation (MR) is uncertain. We …