Musculoskeletal Organs‐on‐Chips: An Emerging Platform for Studying the Nanotechnology–Biology Interface

Y Wang, P Yung, G Lu, Y Liu, C Ding, C Mao… - Advanced …, 2024 - Wiley Online Library
Nanotechnology‐based approaches are promising for the treatment of musculoskeletal
(MSK) disorders, which present significant clinical burdens and challenges, but their clinical …

No sign of weakness: a systematic review and meta-analysis of hip and calf muscle strength after anterior cruciate ligament injury

M Girdwood, AG Culvenor, B Patterson… - British Journal of …, 2024 - bjsm.bmj.com
Objective We aimed to determine hip and lower-leg muscle strength in people after ACL
injury compared with an uninjured control group (between people) and the uninjured …

Self-Administered Acupressure for Probable Knee Osteoarthritis in Middle-Aged and Older Adults: A Randomized Clinical Trial

WF Yeung, SC Chen, DST Cheung… - JAMA Network …, 2024 - jamanetwork.com
Importance The effects of self-administered acupressure (SAA) on knee osteoarthritis (OA)
pain remain unclear. Objective To evaluate the effectiveness of SAA taught via a short …

Recruitment and baseline characteristics of young adults at risk of early-onset knee osteoarthritis after ACL reconstruction in the SUPER-Knee trial

AG Culvenor, TJ West, AM Bruder… - BMJ Open Sport & …, 2024 - bmjopensem.bmj.com
Objectives The study aims to (1) report the process of recruiting young adults into a
secondary knee osteoarthritis prevention randomised controlled trial (RCT) after anterior …

A Self‐Powered Dual Ratchet Angle Sensing System for Digital Twins and Smart Healthcare

C Liu, R Gu, J Yang, L Luo, M Chen… - Advanced Functional …, 2024 - Wiley Online Library
In the swiftly progressing landscape of wearable electronics and the Internet of Things
(IoTs), there is a burgeoning demand for devices that are lightweight, cost‐effective, and self …

Knee confidence, fear of movement, and psychological readiness for sport in individuals with knee conditions: A systematic review with meta-analysis

HF Hart, KM Crossley, AG Culvenor, MCM Khan… - Journal of Orthopaedic & …, 2024 - jospt.org
OBJECTIVE: To (i) compare activity-related psychological factors between individuals with
and without knee conditions, and (ii) assess associations between these factors and …

Modulating synovial macrophage pyroptosis and mitophagy interactions to mitigate osteoarthritis progression using functionalized nanoparticles

W Qi, L Jin, S Huang, A Aikebaier, S Xue, QY Wang… - Acta Biomaterialia, 2024 - Elsevier
Synovial macrophages play an important role in the progression of osteoarthritis (OA). In this
study, we noted that synovial macrophages can activate pyroptosis in a gasdermin d …

Spermidine ameliorates osteoarthritis via altering macrophage polarization

Q Ou, J Zhu, S Xue, H Huang, Y Zhao, Y Cai… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Objective Spermidine (SPD) is an anti-aging natural substance, and it exerts effects through
anti-apoptosis and anti-inflammation. However, the specific protective mechanism of SPD in …

Bone and Joint‐on‐Chip Platforms: Construction Strategies and Applications

C Du, J Liu, S Liu, P Xiao, Z Chen, H Chen… - Small …, 2024 - Wiley Online Library
Abstract Organ‐on‐a‐chip, also known as “tissue chip,” is an advanced platform based on
microfluidic systems for constructing miniature organ models in vitro. They can replicate the …

Composite Zonal Scaffolds of Collagen I/II for Meniscus Regeneration

MI González-Duque, AM Flórez… - ACS Biomaterials …, 2024 - ACS Publications
The meniscus is divided into three zones according to its vascularity: an external
vascularized red–red zone mainly comprising collagen I, a red–white interphase zone …