Breast cancer is a complex disease encompassing multiple tumor entities, each
characterized by distinct morphology, behavior and clinical implications. Besides estrogen …

Breast cancer accounts for 25% of all types of cancer in women, and triple negative breast
cancer (TNBC) comprises around 15~ 20% of breast cancers. Conventional chemotherapy …

We have summarized the evolution of the Nurses' Health Study (NHS), a prospective cohort
study of 121 700 married registered nurses launched in 1976; NHS II, which began in 1989 …

Breast cancer is the second leading cause of cancer death in women, affecting 1.7 million
patients every year worldwide. As a result of its heterogeneous nature, the genetic profile …

Summary Heat-Shock Factor 1 (HSF1), master regulator of the heat-shock response,
facilitates malignant transformation, cancer cell survival, and proliferation in model systems …

Introduction The androgen receptor (AR) is widely expressed in breast cancers and has
been proposed as a therapeutic target in estrogen receptor alpha (ER) negative breast …

Despite significant progress in breast cancer (BC) therapy, it is globally the most commonly
diagnosed cancer and leads to the death of over 650,000 women annually. Androgen …

Background The androgen receptor (AR) is expressed frequently in breast cancer, but its
prognostic significance is unclear. Preclinical data suggest that expression of AR may …

Importance The androgen receptor (AR) pathway is emerging as a potential therapeutic
target in breast cancer. To date, AR-targeted drugs have been approved only for treatment of …

The Androgen Receptor (AR) is emerging as an important factor in the pathogenesis of
breast cancer (BC), which is the most common malignancy among females worldwide. The …