Mesenchymal stem cell secretome or conditioned medium (MSC-CM) is a combination of
biomolecules and growth factors in cell culture growth medium, secreted by mesenchymal …

Since material stiffness controls many cell functions, we reviewed the currently available
knowledge on stiffness sensing and elucidated what is known in the context of clinical and …

Biomaterials to facilitate the restoration of cardiac tissue is of emerging importance. While
there are many aspects to consider in the design of biomaterials, mechanical properties can …

Mesenchymal stem cells (MSCs), as a kind of pluripotent stem cells, have attracted much
attention in orthopedic diseases, geriatric diseases, metabolic diseases, and sports …

Acute myocardial infarction (AMI) remains the main cause of mortality worldwide. Despite
surgery and medical treatment, the non‑regeneration of dead cardiomyocytes and the …

Osteoarthritis (OA) is the most common debilitating joint disease, yet there is no curative
treatment for OA to date. Delivering mesenchymal stromal cells (MSCs) as therapeutic cells …

Abstract Objectives Mesenchymal stem cells (MSCs) based therapy for bone regeneration
has been regarded as a promising method in the clinic. However, hBMSCs with invasive …

Introduction Despite tremendous advances, the shortcomings of current therapies for
coronary disease are evidenced by the fact that it remains the leading cause of death in …

The activity of stem cell processes is regulated by internal and external signals of the cell
“niche”. In general, the niche of stem cells can be represented as the microenvironment of …

The stiffness of extracellular matrix is dynamically stiffened during bone formation. Paracrine
of angiogenic factors in mesenchymal stem cells (MSCs) plays an essential role during …